4OHT
Crystal structure of succinic semialdehyde dehydrogenase from Streptococcus pyogenes in complex with NADP+ as the cofactor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| A | 0004777 | molecular_function | succinate-semialdehyde dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0036243 | molecular_function | succinate-semialdehyde dehydrogenase (NADP+) activity |
| B | 0004030 | molecular_function | aldehyde dehydrogenase [NAD(P)+] activity |
| B | 0004777 | molecular_function | succinate-semialdehyde dehydrogenase (NAD+) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0036243 | molecular_function | succinate-semialdehyde dehydrogenase (NADP+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE NAP A 501 |
| Chain | Residue |
| A | VAL128 |
| A | SER208 |
| A | GLY211 |
| A | SER214 |
| A | ILE215 |
| A | HOH631 |
| A | HOH668 |
| A | HOH738 |
| A | HOH745 |
| A | HOH763 |
| A | HOH825 |
| A | GLU129 |
| A | HOH895 |
| A | PRO130 |
| A | TRP131 |
| A | LYS155 |
| A | HIS156 |
| A | ALA157 |
| A | SER158 |
| A | TYR188 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE NAP B 501 |
| Chain | Residue |
| B | VAL128 |
| B | GLU129 |
| B | PRO130 |
| B | TRP131 |
| B | LYS155 |
| B | HIS156 |
| B | ALA157 |
| B | SER158 |
| B | TYR188 |
| B | THR206 |
| B | SER208 |
| B | GLY211 |
| B | SER214 |
| B | ILE215 |
| B | HOH662 |
| B | HOH671 |
| B | HOH715 |
| B | HOH717 |
| B | HOH792 |
| B | HOH837 |
| B | HOH849 |
