4OCC
co-crystal structure of MDM2(17-111) in complex with compound 48
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005634 | cellular_component | nucleus |
A | 0043066 | biological_process | negative regulation of apoptotic process |
A | 0051726 | biological_process | regulation of cell cycle |
C | 0005634 | cellular_component | nucleus |
C | 0043066 | biological_process | negative regulation of apoptotic process |
C | 0051726 | biological_process | regulation of cell cycle |
E | 0005634 | cellular_component | nucleus |
E | 0043066 | biological_process | negative regulation of apoptotic process |
E | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE 2TZ A 201 |
Chain | Residue |
A | LEU54 |
A | HOH383 |
E | GLN18 |
E | ARG97 |
E | HOH319 |
A | GLY58 |
A | GLN59 |
A | ILE61 |
A | VAL93 |
A | LYS94 |
A | HIS96 |
A | ILE99 |
A | TYR100 |
site_id | AC2 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE 2TZ C 201 |
Chain | Residue |
A | HOH345 |
C | LEU54 |
C | GLY58 |
C | GLN59 |
C | ILE61 |
C | VAL93 |
C | LYS94 |
C | HIS96 |
C | ILE99 |
C | TYR100 |
C | HOH332 |
C | HOH397 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE 2TZ E 201 |
Chain | Residue |
C | ARG97 |
E | LEU54 |
E | VAL93 |
E | LYS94 |
E | HIS96 |
E | TYR100 |
E | HOH343 |