4O8Y

Zinc-free Rpn11 in complex with Rpn8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
B	0008233	molecular_function	peptidase activity
B	0008237	molecular_function	metallopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 201

Chain	Residue
A	ILE83
B	HIS40
B	ALA43

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 202

Chain	Residue
A	ASN50
A	EDO207
A	HOH366
A	HOH374
B	HOH476

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 203

Chain	Residue
A	ILE83
A	ALA85
A	LYS81

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 204

Chain	Residue
A	ARG100
A	ALA101
A	ASP103
A	LEU104
A	PHE154
A	HOH384
B	GLN145

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 205

Chain	Residue
A	PRO97
A	LYS98
A	LEU99
A	ASP135
A	TYR137

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 206

Chain	Residue
A	ASP64
A	TRP66

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 207

Chain	Residue
A	CYS80
A	ILE83
A	EDO202
A	HOH310
A	HOH334

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 208

Chain	Residue
A	ASP20
A	GLU23
A	HOH307
A	HOH365
B	GLU209
B	HOH409

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 209

Chain	Residue
A	GLU57
A	PHE67

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 210

Chain	Residue
A	TYR22
A	GLU29
A	LYS31
A	ARG32
A	SER95
A	GLY96
B	TRP117

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 211

Chain	Residue
A	GLU78
A	MET79
A	LYS82
A	HOH343
B	HOH483

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO B 301

Chain	Residue
B	VAL83
B	GLN88
B	LEU132

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 302

Chain	Residue
A	LYS98
A	ASP124
A	HOH423
A	HOH439
B	TYR196
B	HOH467

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO B 303

Chain	Residue
B	ILE153
B	HOH413
B	HOH470

---

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 304

Chain	Residue
B	SER198
B	ASN200

---

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 305

Chain	Residue
A	ALA166
B	ARG42
B	PRO143
B	SER146
B	HOH474
B	HOH475
B	HOH525

---

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 306

Chain	Residue
A	LYS112
A	THR114
A	HOH421
B	PHE57
B	VAL58
B	ARG135

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 307

Chain	Residue
A	GLU108
A	LYS111
A	ASN117
A	ALA139
A	LYS152
A	HOH406

---

site_id	CC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 308

Chain	Residue
B	PRO72
B	GLN73
B	SER74
B	VAL78
B	ALA82
B	HOH401
B	HOH459

---

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 309

Chain	Residue
B	MET214
B	HIS217

---

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO B 310

Chain	Residue
B	LYS96
B	GLY99
B	HOH482

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	135
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"12504901","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Motif: {"description":"JAMM motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---