4O8A

First structure of a proline utilization A proline dehydrogenase domain

Replaces:  1K87

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003842	molecular_function	L-glutamate gamma-semialdehyde dehydrogenase activity
A	0004657	molecular_function	proline dehydrogenase activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006562	biological_process	L-proline catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	34
Details	BINDING SITE FOR RESIDUE FAD A 2001

Chain	Residue
A	ASP370
A	ALA436
A	TYR437
A	TRP438
A	TYR456
A	THR457
A	ARG458
A	LYS459
A	THR462
A	ALA485
A	THR486
A	ALA371
A	HIS487
A	ASN488
A	CYS512
A	LEU513
A	TYR540
A	ARG556
A	GLU559
A	SER565
A	PHE566
A	2OP2002
A	VAL402
A	HOH2106
A	HOH2113
A	HOH2138
A	HOH2141
A	HOH2227
A	GLN404
A	TYR406
A	ARG431
A	VAL433
A	LYS434
A	GLY435

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 2OP A 2002

Chain	Residue
A	LYS329
A	ASP370
A	ALA436
A	TYR540
A	TYR552
A	ARG555
A	ARG556
A	FAD2001
A	HOH2128

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PG4 A 2003

Chain	Residue
A	THR422
A	ARG425
A	ARG426
A	LEU474
A	ASN478
A	LEU498

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PG4 A 2004

Chain	Residue
A	MET255
A	ASN560

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