Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009236 | biological_process | cobalamin biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE UDP A 301 |
| Chain | Residue |
| A | GLU89 |
| A | ARG198 |
| A | ARG214 |
| A | PO4305 |
| A | HOH443 |
| A | HOH449 |
| A | HOH481 |
| A | ARG93 |
| A | GLY98 |
| A | SER99 |
| A | ASP173 |
| A | LYS175 |
| A | ASP195 |
| A | THR196 |
| A | CYS197 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ADP A 302 |
| Chain | Residue |
| A | LYS13 |
| A | MET15 |
| A | HIS68 |
| A | GLU81 |
| A | LEU83 |
| A | MET85 |
| A | LYS122 |
| A | LYS175 |
| A | GLU177 |
| A | ALA189 |
| A | ASP190 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE U5P A 303 |
| Chain | Residue |
| A | GLU89 |
| A | ARG93 |
| A | GLY98 |
| A | SER99 |
| A | ASP173 |
| A | LYS175 |
| A | ASP195 |
| A | THR196 |
| A | CYS197 |
| A | ARG198 |
| A | ARG214 |
| A | HOH443 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 304 |
| Chain | Residue |
| A | ARG103 |
| A | ARG103 |
| A | MET130 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 305 |
| Chain | Residue |
| A | THR32 |
| A | ALA33 |
| A | PHE34 |
| A | LYS210 |
| A | ARG214 |
| A | UDP301 |
| A | HOH449 |
Functional Information from PROSITE/UniProt
| site_id | PS01057 |
| Number of Residues | 15 |
| Details | SAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. MYPLEvVVRnvvAGS |
| Chain | Residue | Details |
| A | MET85-SER99 | |
| site_id | PS01058 |
| Number of Residues | 9 |
| Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. LVDfKLEFG |
| Chain | Residue | Details |
| A | LEU171-GLY179 | |
