4O4Y

Crystal structure of the anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL L 401

Chain	Residue
H	HIS165
L	THR170
L	GLU171
L	ASP173
L	HOH545
L	HOH568

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL L 402

Chain	Residue
L	TYR88
L	GLY105
L	GLY106
L	LYS108
L	HOH699
H	GLY41
H	LYS42
L	SER8

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 301

Chain	Residue
H	GLY64
H	PHE66
H	ILE67
H	ASP100
L	TYR50
L	LEU55
L	ALA56
L	SER57

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL H 302

Chain	Residue
H	SER6
H	GLY7

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL H 303

Chain	Residue
H	VAL153
H	THR166
H	HOH554
H	HOH646

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site_id	AC6
Number of Residues	27
Details	BINDING SITE FOR CHAIN A OF IDES HINGE PEPTIDE

Chain	Residue
A	HOH301
A	HOH302
A	HOH303
A	HOH304
A	HOH305
A	HOH306
A	HOH308
H	PRO32
H	ASN34
H	GLY49
H	GLY51
H	SER53
H	ASN55
H	TRP57
H	GLY96
H	LEU97
H	TYR98
H	ASN99
H	TYR101
L	TYR29
L	TYR93
L	ASP94
L	CYS95
L	ASN96
L	HIS101
L	HOH503
L	HOH536

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR198-HIS204
H	TYR195-HIS201

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