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4NYX

Crystal Structure of the Bromodomain of human CREBBP in complex with a dihydroquinoxalinone ligand

Functional Information from GO Data
ChainGOidnamespacecontents
A0004402molecular_functionhistone acetyltransferase activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE 2O4 A 1201
ChainResidue
APRO1110
AHOH1433
AVAL1115
ALEU1120
AASN1168
AARG1173
AVAL1174
AHOH1302
AHOH1346
AHOH1389

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues60
DetailsBROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY
ChainResidueDetails
ASER1108-TYR1167

218853

PDB entries from 2024-04-24

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