4NV1
Crystal structure of a 4-N formyltransferase from Francisella tularensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004479 | molecular_function | methionyl-tRNA formyltransferase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006413 | biological_process | translational initiation |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0071951 | biological_process | conversion of methionyl-tRNA to N-formyl-methionyl-tRNA |
| B | 0004479 | molecular_function | methionyl-tRNA formyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006413 | biological_process | translational initiation |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0071951 | biological_process | conversion of methionyl-tRNA to N-formyl-methionyl-tRNA |
| C | 0004479 | molecular_function | methionyl-tRNA formyltransferase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006413 | biological_process | translational initiation |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0071951 | biological_process | conversion of methionyl-tRNA to N-formyl-methionyl-tRNA |
| D | 0004479 | molecular_function | methionyl-tRNA formyltransferase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006413 | biological_process | translational initiation |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0071951 | biological_process | conversion of methionyl-tRNA to N-formyl-methionyl-tRNA |
| E | 0004479 | molecular_function | methionyl-tRNA formyltransferase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0006413 | biological_process | translational initiation |
| E | 0009058 | biological_process | biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0071951 | biological_process | conversion of methionyl-tRNA to N-formyl-methionyl-tRNA |
| F | 0004479 | molecular_function | methionyl-tRNA formyltransferase activity |
| F | 0005829 | cellular_component | cytosol |
| F | 0006413 | biological_process | translational initiation |
| F | 0009058 | biological_process | biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0071951 | biological_process | conversion of methionyl-tRNA to N-formyl-methionyl-tRNA |
| G | 0004479 | molecular_function | methionyl-tRNA formyltransferase activity |
| G | 0005829 | cellular_component | cytosol |
| G | 0006413 | biological_process | translational initiation |
| G | 0009058 | biological_process | biosynthetic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0071951 | biological_process | conversion of methionyl-tRNA to N-formyl-methionyl-tRNA |
| H | 0004479 | molecular_function | methionyl-tRNA formyltransferase activity |
| H | 0005829 | cellular_component | cytosol |
| H | 0006413 | biological_process | translational initiation |
| H | 0009058 | biological_process | biosynthetic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0071951 | biological_process | conversion of methionyl-tRNA to N-formyl-methionyl-tRNA |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 0FX C 301 |
| Chain | Residue |
| C | ASN10 |
| C | TYR218 |
| C | ASN220 |
| C | HOH494 |
| C | HIS73 |
| C | SER74 |
| C | LYS75 |
| C | TRP102 |
| C | PHE103 |
| C | GLN105 |
| C | TYR149 |
| C | HIS215 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 C 302 |
| Chain | Residue |
| C | ASP225 |
| C | GLU226 |
| C | HOH481 |
| D | ARG204 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TYD D 301 |
| Chain | Residue |
| D | ASN10 |
| D | HIS73 |
| D | PHE103 |
| D | GLN105 |
| D | TYR149 |
| D | HIS215 |
| D | TYR218 |
| D | ASN220 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 0FX E 301 |
| Chain | Residue |
| E | ASN10 |
| E | HIS73 |
| E | LYS75 |
| E | PHE103 |
| E | GLN105 |
| E | TYR149 |
| E | HIS215 |
| E | TYR218 |
| E | ASN220 |
| E | HOH402 |
| E | HOH417 |
| E | HOH438 |
| E | HOH478 |
| E | HOH486 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TYD F 301 |
| Chain | Residue |
| F | ASN10 |
| F | HIS73 |
| F | PHE103 |
| F | GLN105 |
| F | TYR149 |
| F | HIS215 |
| F | TYR218 |
| F | ASN220 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 F 302 |
| Chain | Residue |
| E | ASP225 |
| E | GLU226 |
| F | ARG204 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 4TG B 301 |
| Chain | Residue |
| B | ASN10 |
| B | HIS73 |
| B | SER74 |
| B | LYS75 |
| B | TRP102 |
| B | PHE103 |
| B | GLN105 |
| B | TYR149 |
| B | HIS215 |
| B | TYR218 |
| B | ASN220 |
| B | HOH414 |
| B | HOH437 |
| B | HOH445 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 302 |
| Chain | Residue |
| A | ARG204 |
| B | ASP225 |
| B | GLU226 |
| B | HOH468 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 0FX A 301 |
| Chain | Residue |
| A | ASN10 |
| A | HIS73 |
| A | LYS75 |
| A | PHE103 |
| A | GLN105 |
| A | TYR149 |
| A | HIS215 |
| A | TYR218 |
| A | ASN220 |
| A | HOH452 |
| A | HOH477 |
| A | HOH515 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 0FX G 301 |
| Chain | Residue |
| G | ASN10 |
| G | HIS73 |
| G | LYS75 |
| G | TRP102 |
| G | PHE103 |
| G | GLN105 |
| G | TYR149 |
| G | TYR189 |
| G | HIS215 |
| G | TYR218 |
| G | ASN220 |
| G | HOH418 |
| site_id | BC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE TYD H 301 |
| Chain | Residue |
| H | HOH439 |
| H | HOH464 |
| H | HIS73 |
| H | PHE103 |
| H | GLN105 |
| H | TYR149 |
| H | HIS215 |
| H | TYR218 |
| H | ASN220 |
| H | HOH428 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 H 302 |
| Chain | Residue |
| G | ARG204 |
| H | LEU197 |
| H | ASP225 |
| H | GLU226 |
| H | HOH497 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 H 303 |
| Chain | Residue |
| G | ASP225 |
| G | GLU226 |
| H | ARG204 |
Functional Information from PROSITE/UniProt
| site_id | PS00373 |
| Number of Residues | 24 |
| Details | GART Phosphoribosylglycinamide formyltransferase active site. GaTIhVMdEeIDhGdiIiqeeveV |
| Chain | Residue | Details |
| C | GLY116-VAL139 |
