Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4NTK

QueD from E. coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
A	0008616	biological_process	queuosine biosynthetic process
A	0016829	molecular_function	lyase activity
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
B	0008270	molecular_function	zinc ion binding
B	0008616	biological_process	queuosine biosynthetic process
B	0016829	molecular_function	lyase activity
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
C	0008270	molecular_function	zinc ion binding
C	0008616	biological_process	queuosine biosynthetic process
C	0016829	molecular_function	lyase activity
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
D	0008270	molecular_function	zinc ion binding
D	0008616	biological_process	queuosine biosynthetic process
D	0016829	molecular_function	lyase activity
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
E	0008270	molecular_function	zinc ion binding
E	0008616	biological_process	queuosine biosynthetic process
E	0016829	molecular_function	lyase activity
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
E	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
F	0008270	molecular_function	zinc ion binding
F	0008616	biological_process	queuosine biosynthetic process
F	0016829	molecular_function	lyase activity
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
F	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	HIS16
A	HIS31
A	HIS33
A	ZSP202

site_id	AC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ZSP A 202

Chain	Residue
A	GLU86
A	GLU110
A	ZN201
C	HIS71
E	LEU6
E	TRP51
E	ILE53
E	ASP54
E	PHE55
A	HIS16
A	HIS31
A	HIS33
A	THR84
A	SER85

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 203

Chain	Residue
A	LYS8
A	LYS59
A	HOH371

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 201

Chain	Residue
B	HIS16
B	HIS31
B	HIS33
B	ZSP202

site_id	AC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ZSP B 202

Chain	Residue
A	LEU6
A	TRP51
A	ILE53
A	ASP54
A	PHE55
B	HIS16
B	LEU18
B	LYS26
B	HIS31
B	HIS33
B	THR84
B	SER85
B	GLU86
B	GLU110
B	ZN201
D	HIS71

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT B 203

Chain	Residue
B	LYS8
B	LYS59
B	HOH371
E	LYS26

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 201

Chain	Residue
C	HIS16
C	HIS31
C	HIS33
C	ZSP202

site_id	AC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ZSP C 202

Chain	Residue
A	HIS71
C	HIS16
C	LEU18
C	LYS26
C	ALA27
C	HIS31
C	HIS33
C	THR84
C	SER85
C	GLU86
C	GLU110
C	ZN201
D	LEU6
D	TRP51
D	ILE53
D	ASP54
D	PHE55

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT C 203

Chain	Residue
C	LYS8
C	LYS59
C	HOH371

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 201

Chain	Residue
D	HIS16
D	HIS31
D	HIS33
D	ZSP202

site_id	BC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ZSP D 202

Chain	Residue
B	HIS71
D	HIS16
D	LYS26
D	ALA27
D	HIS31
D	HIS33
D	THR84
D	SER85
D	GLU86
D	GLU110
D	ZN201
F	LEU6
F	TRP51
F	ILE53
F	ASP54
F	PHE55

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT D 203

Chain	Residue
D	LYS8
D	LYS59
D	HOH360

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 201

Chain	Residue
E	HIS16
E	HIS31
E	HIS33
E	ZSP202

site_id	BC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ZSP E 202

Chain	Residue
B	ASP54
B	PHE55
B	HOH359
E	HIS16
E	ALA27
E	HIS31
E	HIS33
E	THR84
E	SER85
E	GLU86
E	GLU110
E	ZN201
F	HIS71
B	LEU6
B	TRP51
B	ILE53

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT E 203

Chain	Residue
E	LYS8
E	LYS59
E	HOH367
E	HOH373

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 201

Chain	Residue
F	HIS16
F	HIS31
F	HIS33
F	ZSP202

site_id	BC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ZSP F 202

Chain	Residue
C	LEU6
C	TRP51
C	ILE53
C	ASP54
C	PHE55
E	HIS71
F	HIS16
F	LYS26
F	ALA27
F	HIS31
F	HIS33
F	THR84
F	SER85
F	GLU86
F	GLU110
F	ZN201

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	ALA27
B	ALA27
C	ALA27
D	ALA27
E	ALA27
F	ALA27

site_id	SWS_FT_FI2
Number of Residues	12
Details	ACT_SITE: Charge relay system => ECO:0000250

Chain	Residue	Details
A	HIS71
E	GLU110
F	HIS71
F	GLU110
A	GLU110
B	HIS71
B	GLU110
C	HIS71
C	GLU110
D	HIS71
D	GLU110
E	HIS71

site_id	SWS_FT_FI3
Number of Residues	18
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	HIS16
D	HIS16
D	HIS31
D	HIS33
E	HIS16
E	HIS31
E	HIS33
F	HIS16
F	HIS31
F	HIS33
A	HIS31
A	HIS33
B	HIS16
B	HIS31
B	HIS33
C	HIS16
C	HIS31
C	HIS33

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)