4NRP

Crystal structure of human ALKBH5 in complex with N-oxalylglycine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006397	biological_process	mRNA processing
A	0035515	molecular_function	oxidative RNA demethylase activity
A	0035553	biological_process	obsolete oxidative single-stranded RNA demethylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 301

Chain	Residue
A	HIS204
A	ASP206
A	HIS266
A	OGA302

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE OGA A 302

Chain	Residue
A	HIS266
A	ILE268
A	ARG277
A	VAL279
A	ILE281
A	MN301
A	HOH436
A	LYS132
A	ASN193
A	TYR195
A	HIS204
A	ASP206

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:24778178

Chain	Residue	Details
A	ASN193
A	ARG277

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:24616105, ECO:0000305|PubMed:24778178

Chain	Residue	Details
A	HIS204
A	ASP206
A	HIS266

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER69

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	TYR71

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS132

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