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4NR6

Crystal structure of the bromodomain of human CREBBP in complex with an oxazepin ligand

Functional Information from GO Data
ChainGOidnamespacecontents
A0004402molecular_functionhistone acetyltransferase activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE 2LN A 1201
ChainResidue
ALEU1109
AHOH1305
AHOH1361
AHOH1397
AHOH1398
APRO1110
APHE1111
AVAL1115
ALEU1120
AASN1168
AARG1173
AVAL1174
AGLU1186

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues60
DetailsBROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY
ChainResidueDetails
ASER1108-TYR1167

222415

PDB entries from 2024-07-10

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