4NPY
Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL L 301 |
| Chain | Residue |
| B | LYS206 |
| L | LYS149 |
| L | ASP151 |
| L | SER152 |
| L | SER192 |
| L | GLU203 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL H 301 |
| Chain | Residue |
| H | LYS209 |
| L | GLU123 |
| H | SER120 |
| H | VAL121 |
| H | VAL207 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 301 |
| Chain | Residue |
| A | TYR49 |
| A | PRO55 |
| A | SER56 |
| B | TYR100 |
| B | ASP101 |
| B | HOH460 |
| B | HOH553 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH |
| Chain | Residue | Details |
| L | TYR191-HIS197 | |
| H | TYR194-HIS200 |
