4NNU
Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 136 |
| Details | DNA_BIND: HMG box 1 => ECO:0000255|PROSITE-ProRule:PRU00267 |
| Chain | Residue | Details |
| A | PRO50-LYS118 | |
| B | PRO50-LYS118 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 128 |
| Details | DNA_BIND: HMG box 2 => ECO:0000255|PROSITE-ProRule:PRU00267 |
| Chain | Residue | Details |
| A | PRO155-GLU219 | |
| B | PRO155-GLU219 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Intercalates between bases and promotes DNA bending |
| Chain | Residue | Details |
| A | LEU58 | |
| A | LEU182 | |
| B | LEU58 | |
| B | LEU182 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:23201127 |
| Chain | Residue | Details |
| A | SER55 | |
| A | SER56 | |
| A | SER61 | |
| A | SER160 | |
| B | SER55 | |
| B | SER56 | |
| B | SER61 | |
| B | SER160 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | THR122 | |
| B | THR122 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER193 | |
| B | SER193 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER195 | |
| B | SER195 |
