4NN5

Cytokine receptor complex - Crystal form 1A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001961	biological_process	positive regulation of cytokine-mediated signaling pathway
A	0005125	molecular_function	cytokine activity
A	0005139	molecular_function	interleukin-7 receptor binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0007165	biological_process	signal transduction
A	0032722	biological_process	positive regulation of chemokine production
A	0032733	biological_process	positive regulation of interleukin-10 production
A	0032736	biological_process	positive regulation of interleukin-13 production
A	0032754	biological_process	positive regulation of interleukin-5 production
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
A	0050729	biological_process	positive regulation of inflammatory response
A	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
B	0004896	molecular_function	cytokine receptor activity
B	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS01355
Number of Residues	33
Details	HEMATOPO_REC_S_F1 Short hematopoietin receptor family 1 signature. LrpkamyeikVRsiphndyfkgf.........WSeWSpsstF

Chain	Residue	Details
B	LEU195-PHE227

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24632570

Chain	Residue	Details
C	ASN53

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
C	GLN122
B	ASN115
B	ASN177

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