Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ADP A 401 |
| Chain | Residue |
| A | ASN64 |
| A | TYR134 |
| A | VAL135 |
| A | THR138 |
| A | ARG141 |
| A | GLN185 |
| A | ASN186 |
| A | LEU188 |
| A | ASP200 |
| A | MG405 |
| A | MG406 |
| A | PHE67 |
| A | HOH539 |
| A | HOH566 |
| A | HOH582 |
| A | GLY68 |
| A | VAL70 |
| A | ALA83 |
| A | LYS85 |
| A | VAL110 |
| A | LEU132 |
| A | ASP133 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | TYR56 |
| A | LYS86 |
| A | SER118 |
| A | ASN129 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | ARG144 |
| A | SER147 |
| A | ARG148 |
| A | LEU252 |
| A | GLN254 |
| A | PRO255 |
| A | VAL304 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 404 |
| Chain | Residue |
| A | ARG148 |
| A | LYS271 |
| A | HIS299 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 405 |
| Chain | Residue |
| A | ASP200 |
| A | ADP401 |
| A | HOH513 |
| A | HOH539 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 406 |
| Chain | Residue |
| A | ASN186 |
| A | ASP200 |
| A | ADP401 |
| A | HOH571 |
| A | HOH582 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 407 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DTT A 408 |
| Chain | Residue |
| A | ARG319 |
| A | THR326 |
| A | ALA327 |
| A | ARG328 |
| A | GLU333 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGNGSFGVVYqAklcdsgelv.........AIKK |
| Chain | Residue | Details |
| A | ILE62-LYS86 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IcHrDIKpqNLLL |
| Chain | Residue | Details |
| A | ILE177-LEU189 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17050006","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"12554650","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25169422","evidenceCode":"ECO:0000269"}]} |
