4NLT

Poliovirus Polymerase - S291P Loop Mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACY A 901

Chain	Residue
A	TRP403
A	THR404
A	THR410
A	HIS413
A	HOH1126

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACY A 903

Chain	Residue
A	HOH1067
A	TYR334
A	HIS336
A	PRO440
A	ARG443

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACY A 904

Chain	Residue
A	ARG379

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE 1PE A 906

Chain	Residue
A	SER219
A	LYS220
A	LEU387
A	PHE461

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE 1PE A 907

Chain	Residue
A	PHE378

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE 1PE A 908

Chain	Residue
A	GLU227
A	LYS228
A	GLU337
A	THR365

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 1PE A 909

Chain	Residue
A	TYR326
A	ARG376
A	HOH1057

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 910

Chain	Residue
A	LEU268
A	ASN269
A	SER271
A	GLY284
A	GLY285
A	HOH1082

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21148772","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21148772","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2196557","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---