Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005007 | molecular_function | fibroblast growth factor receptor activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005007 | molecular_function | fibroblast growth factor receptor activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 801 |
Chain | Residue |
A | ARG570 |
A | ARG627 |
A | THR657 |
A | ASN659 |
A | ARG661 |
A | TRP666 |
A | HOH915 |
A | HOH990 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 802 |
Chain | Residue |
A | LYS540 |
A | LYS618 |
A | HOH987 |
A | GLY539 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 803 |
Chain | Residue |
A | ALA615 |
A | THR746 |
A | PHE747 |
A | LYS748 |
A | HOH933 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 804 |
Chain | Residue |
A | TRP684 |
A | TYR701 |
A | ARG718 |
A | MET719 |
A | TRP737 |
A | HOH919 |
site_id | AC5 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE 2K7 A 805 |
Chain | Residue |
A | LEU484 |
A | ALA512 |
A | GLU531 |
A | GLU562 |
A | TYR563 |
A | ALA564 |
A | GLY567 |
A | ARG627 |
A | LEU630 |
A | ASP641 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 801 |
Chain | Residue |
B | ARG570 |
B | ARG627 |
B | THR657 |
B | ASN659 |
B | ARG661 |
B | HOH901 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 802 |
Chain | Residue |
B | TYR701 |
B | LEU713 |
B | ARG718 |
B | MET719 |
B | TRP737 |
B | HOH963 |
site_id | AC8 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE 2K7 B 803 |
Chain | Residue |
B | LEU484 |
B | ALA512 |
B | LYS514 |
B | GLU531 |
B | VAL561 |
B | GLU562 |
B | TYR563 |
B | ALA564 |
B | ARG627 |
B | LEU630 |
B | ASP641 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 31 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVlAeaigldkdkpnrvtk...VAVK |
Chain | Residue | Details |
A | LEU484-LYS514 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
Chain | Residue | Details |
A | CYS619-VAL631 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP623 | |
B | ASP623 | |
site_id | SWS_FT_FI2 |
Number of Residues | 12 |
Details | BINDING: |
Chain | Residue | Details |
A | LEU484 | |
B | ASN568 | |
B | ARG627 | |
B | ASP641 | |
A | LYS514 | |
A | GLU562 | |
A | ASN568 | |
A | ARG627 | |
A | ASP641 | |
B | LEU484 | |
B | LYS514 | |
B | GLU562 | |
Chain | Residue | Details |
A | TYR463 | |
A | TYR583 | |
A | TYR585 | |
B | TYR463 | |
B | TYR583 | |
B | TYR585 | |
Chain | Residue | Details |
A | TYR653 | |
A | TYR654 | |
B | TYR653 | |
B | TYR654 | |
Chain | Residue | Details |
A | TYR730 | |
B | TYR730 | |