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4NHO

Structure of the spliceosomal DEAD-box protein Prp28

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0003724molecular_functionRNA helicase activity
A0005524molecular_functionATP binding
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 A 901
ChainResidue
ATHR437
AGLY438
ASER439
AGLY440
ALYS441
ATHR442
AHOH1025

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 A 902
ChainResidue
AARG508
ATHR525
AGLY527
AARG528
AHOH1033
AGLY504
AGLY505

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 903
ChainResidue
APRO457
ALYS458
AHOH1110
AHOH1158

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 904
ChainResidue
AGLY384
ALYS385
ALYS760
AHOH1157

site_idAC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 A 905
ChainResidue
ALYS382
AHOH1209

site_idAC6
Number of Residues9
DetailsBINDING SITE FOR RESIDUE GOL A 906
ChainResidue
AGLN564
ALEU567
AGLU568
AARG615
ALEU616
ASER619
ATYR620
AHOH1161
AHOH1197

site_idAC7
Number of Residues2
DetailsBINDING SITE FOR RESIDUE GOL A 907
ChainResidue
AGLN781
AGLU785

site_idAC8
Number of Residues8
DetailsBINDING SITE FOR RESIDUE CXS A 908
ChainResidue
AHIS356
AASP376
ATYR377
AASN672
AGLN673
ALYS674
AVAL723
AASP747

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE HG A 909
ChainResidue
AILE472
ALEU540
ACYS543
ATYR545
AVAL546
AMET570

Functional Information from PROSITE/UniProt
site_idPS00039
Number of Residues9
DetailsDEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADRmI
ChainResidueDetails
AVAL547-ILE555

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541
ChainResidueDetails
AALA435

site_idSWS_FT_FI2
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS686
ALYS811

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PDB entries from 2024-11-06

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