4NC9

Crystal structure of phosphatidyl mannosyltransferase PimA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004377	molecular_function	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
A	0005886	cellular_component	plasma membrane
A	0008654	biological_process	phospholipid biosynthetic process
A	0009247	biological_process	glycolipid biosynthetic process
A	0016757	molecular_function	glycosyltransferase activity
A	0043750	molecular_function	phosphatidylinositol alpha-mannosyltransferase activity
A	0046488	biological_process	phosphatidylinositol metabolic process
A	0046506	biological_process	sulfolipid biosynthetic process
A	0046510	molecular_function	UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity
B	0004377	molecular_function	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
B	0005886	cellular_component	plasma membrane
B	0008654	biological_process	phospholipid biosynthetic process
B	0009247	biological_process	glycolipid biosynthetic process
B	0016757	molecular_function	glycosyltransferase activity
B	0043750	molecular_function	phosphatidylinositol alpha-mannosyltransferase activity
B	0046488	biological_process	phosphatidylinositol metabolic process
B	0046506	biological_process	sulfolipid biosynthetic process
B	0046510	molecular_function	UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity
C	0004377	molecular_function	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
C	0005886	cellular_component	plasma membrane
C	0008654	biological_process	phospholipid biosynthetic process
C	0009247	biological_process	glycolipid biosynthetic process
C	0016757	molecular_function	glycosyltransferase activity
C	0043750	molecular_function	phosphatidylinositol alpha-mannosyltransferase activity
C	0046488	biological_process	phosphatidylinositol metabolic process
C	0046506	biological_process	sulfolipid biosynthetic process
C	0046510	molecular_function	UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity
D	0004377	molecular_function	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
D	0005886	cellular_component	plasma membrane
D	0008654	biological_process	phospholipid biosynthetic process
D	0009247	biological_process	glycolipid biosynthetic process
D	0016757	molecular_function	glycosyltransferase activity
D	0043750	molecular_function	phosphatidylinositol alpha-mannosyltransferase activity
D	0046488	biological_process	phosphatidylinositol metabolic process
D	0046506	biological_process	sulfolipid biosynthetic process
D	0046510	molecular_function	UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000305|PubMed:17510062

Chain	Residue	Details
A	TYR9
B	TYR9
C	TYR9
D	TYR9

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site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:17510062, ECO:0000269|PubMed:19520856

Chain	Residue	Details
B	GLY16
B	VAL251
B	LYS256
B	GLU282
C	GLY16
C	VAL251
C	LYS256
C	GLU282
D	GLY16
D	VAL251
D	LYS256
D	GLU282
A	GLY16
A	VAL251
A	LYS256
A	GLU282

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000305|PubMed:19520856

Chain	Residue	Details
C	ARG68
D	GLN18
D	TYR62
D	ARG68
A	GLN18
A	TYR62
A	ARG68
B	GLN18
B	TYR62
B	ARG68
C	GLN18
C	TYR62

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site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:17510062, ECO:0000305|PubMed:19520856

Chain	Residue	Details
C	ARG196
C	ARG201
D	ARG196
D	ARG201
B	ARG201
A	ARG196
A	ARG201
B	ARG196

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site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:17510062

Chain	Residue	Details
A	GLU274
B	GLU274
C	GLU274
D	GLU274

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	SITE: Important for catalytic activity => ECO:0000269|PubMed:17510062

Chain	Residue	Details
A	HIS118
B	HIS118
C	HIS118
D	HIS118

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