4NBS

The structure of aIF2gamma subunit H20F from archaeon Sulfolobus solfataricus complexed with GDPCP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0001731	biological_process	formation of translation preinitiation complex
A	0003743	molecular_function	translation initiation factor activity
A	0003746	molecular_function	translation elongation factor activity
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0006412	biological_process	translation
A	0006413	biological_process	translational initiation
A	0006414	biological_process	translational elongation
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	BINDING SITE FOR RESIDUE GCP A 501

Chain	Residue
A	VAL18
A	GLY96
A	ASN149
A	LYS150
A	ASP152
A	VAL153
A	SER184
A	ALA185
A	LEU186
A	MG502
A	HOH601
A	ASP19
A	HOH608
A	HOH625
A	HOH629
A	HOH630
A	HOH724
A	HOH779
A	HOH789
A	HOH797
A	HOH864
A	PHE20
A	GLY21
A	LYS22
A	THR23
A	THR24
A	MET45
A	THR46

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 502

Chain	Residue
A	THR23
A	THR46
A	GCP501
A	HOH601
A	HOH797

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 503

Chain	Residue
A	LYS212
A	GLN244
A	TRP389
A	SER390

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FMT A 504

Chain	Residue
A	PHE221

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT A 505

Chain	Residue
A	ARG219
A	ALA296
A	HOH709

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT A 506

Chain	Residue
A	LEU312
A	SER364
A	THR365
A	HOH640
A	HOH660

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 507

Chain	Residue
A	THR366
A	LEU367
A	ARG383
A	ARG384

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 508

Chain	Residue
A	ARG43
A	VAL99
A	HOH691
A	HOH713

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT A 509

Chain	Residue
A	VAL223
A	ARG280
A	HOH674

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT A 510

Chain	Residue
A	HOH857
A	HOH893

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT A 511

Chain	Residue
A	ARG352
A	LYS354

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT A 512

Chain	Residue
A	LYS347
A	VAL348
A	ASP349
A	ARG399

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT A 513

Chain	Residue
A	ARG130
A	FMT515
A	HOH787

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT A 514

Chain	Residue
A	TRP33
A	SER35
A	GLU40
A	GLY44
A	MET45
A	THR46
A	HOH797

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT A 515

Chain	Residue
A	ARG130
A	ASP250
A	LYS275
A	FMT513
A	HOH842

---

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT A 516

Chain	Residue
A	GLU252
A	GLU344
A	MET345

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT A 517

Chain	Residue
A	THR103
A	HOH857
A	HOH885

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 518

Chain	Residue
A	VAL151
A	VAL154
A	TRP327
A	ASN328
A	HOH605
A	HOH616

---

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 519

Chain	Residue
A	THR54
A	THR70
A	HOH641
A	HOH653
A	HOH712
A	HOH848

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	199
Details	Domain: {"description":"tr-type G","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Region: {"description":"G1","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Region: {"description":"G2","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Region: {"description":"G3","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Region: {"description":"G4","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Region: {"description":"G5","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25690901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4RD1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25690901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RD1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16407071","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25690901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AHO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q8U082","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---