4N96

E. coli sliding clamp in complex with 6-nitroindazole

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006271	biological_process	DNA strand elongation involved in DNA replication
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0009360	cellular_component	DNA polymerase III complex
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0030174	biological_process	regulation of DNA-templated DNA replication initiation
A	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
A	0042276	biological_process	error-prone translesion synthesis
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0044787	biological_process	bacterial-type DNA replication
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006271	biological_process	DNA strand elongation involved in DNA replication
B	0006974	biological_process	DNA damage response
B	0008408	molecular_function	3'-5' exonuclease activity
B	0009360	cellular_component	DNA polymerase III complex
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0030174	biological_process	regulation of DNA-templated DNA replication initiation
B	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
B	0042276	biological_process	error-prone translesion synthesis
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0044787	biological_process	bacterial-type DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 6NI A 401

Chain	Residue
A	THR172
A	GLY174
A	VAL247
A	SER346
A	VAL360
A	HOH611

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 402

Chain	Residue
A	GLY46
A	THR47
A	GLU202

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 403

Chain	Residue
A	ALA58

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 404

Chain	Residue
A	GLU6
A	HOH587
B	ASP120
B	HOH593

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PEG A 406

Chain	Residue
A	SER192
A	PHE241
A	PRO242
A	ASP243
A	HOH503

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PEG A 407

Chain	Residue
A	TRP122
A	GLN123
A	SER124
A	ARG224
A	HOH539
B	GLN36
B	ALA38
B	HOH510
B	HOH532

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 408

Chain	Residue
A	HIS226
A	ILE231

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 409

Chain	Residue
A	SER181

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA B 401

Chain	Residue
B	GLU6
B	GLY85
B	GLU87
B	HOH680

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	228
Details	Region: {"description":"2","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	120
Details	Region: {"description":"3","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18191219","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18191219","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---