Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4N83

X-ray crystal structure of Streptococcus sanguinis dimanganese(II)-NrdF

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
A	0005829	cellular_component	cytosol
A	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
A	0009263	biological_process	deoxyribonucleotide biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
B	0005829	cellular_component	cytosol
B	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
B	0009263	biological_process	deoxyribonucleotide biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
C	0005829	cellular_component	cytosol
C	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
C	0009263	biological_process	deoxyribonucleotide biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
D	0005829	cellular_component	cytosol
D	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
D	0009263	biological_process	deoxyribonucleotide biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
E	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
E	0005829	cellular_component	cytosol
E	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
E	0009263	biological_process	deoxyribonucleotide biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
F	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
F	0005829	cellular_component	cytosol
F	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
F	0009263	biological_process	deoxyribonucleotide biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
G	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
G	0005829	cellular_component	cytosol
G	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
G	0009263	biological_process	deoxyribonucleotide biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
G	0046872	molecular_function	metal ion binding
H	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
H	0005829	cellular_component	cytosol
H	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
H	0009263	biological_process	deoxyribonucleotide biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 401

Chain	Residue
A	GLU97
A	GLU157
A	GLU191
A	HIS194

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 402

Chain	Residue
A	ASP66
A	GLU97
A	HIS100
A	GLU157
A	GLU191

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 401

Chain	Residue
B	ASP66
B	GLU97
B	HIS100
B	GLU157
B	GLU191
B	HOH521

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN B 402

Chain	Residue
B	GLU97
B	GLU157
B	GLU191
B	HIS194
B	HOH509

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN C 401

Chain	Residue
C	ASP66
C	GLU97
C	HIS100
C	GLU157
C	GLU191

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN C 402

Chain	Residue
C	GLU97
C	GLU157
C	GLU191
C	HIS194

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D 401

Chain	Residue
D	ASP66
D	GLU97
D	HIS100
D	GLU157
D	GLU191

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN D 402

Chain	Residue
D	GLU97
D	GLU157
D	GLU191
D	HIS194

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN E 401

Chain	Residue
E	GLU97
E	GLU157
E	GLU191
E	HIS194

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN E 402

Chain	Residue
E	ASP66
E	GLU97
E	HIS100
E	GLU157
E	GLU191

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN F 401

Chain	Residue
F	ASP66
F	GLU97
F	HIS100
F	GLU157
F	GLU191

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN F 402

Chain	Residue
F	GLU97
F	GLU157
F	GLU191
F	HIS194

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN G 401

Chain	Residue
G	ASP66
G	GLU97
G	HIS100
G	GLU157
G	GLU191

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN G 402

Chain	Residue
G	GLU97
G	GLU157
G	GLU191
G	HIS194

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN H 401

Chain	Residue
H	ASP66
H	GLU97
H	HIS100
H	GLU157
H	GLU191
H	HOH517

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN H 402

Chain	Residue
H	GLU97
H	GLU157
H	GLU191
H	HIS194
H	HOH518

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)