4N71

X-Ray Crystal Structure of 2-amino-1-hydroxyethylphosphonate-bound PhnZ

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
D	0016491	molecular_function	oxidoreductase activity
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
E	0016491	molecular_function	oxidoreductase activity
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 201

Chain	Residue
A	ASP59
A	HIS80
A	HIS104
A	FE202
A	ODV203

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 202

Chain	Residue
A	FE201
A	HIS34
A	HIS58
A	ASP59
A	ASP161

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ODV A 203

Chain	Residue
A	GLU27
A	ASP59
A	HIS62
A	HIS80
A	HIS104
A	LYS108
A	SER126
A	THR129
A	GLN133
A	ARG158
A	FE201

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE B 201

Chain	Residue
B	ASP59
B	HIS80
B	HIS104
B	ASP161
B	FE202
B	ODV203

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE B 202

Chain	Residue
B	HIS34
B	HIS58
B	ASP59
B	ASP161
B	FE201

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ODV B 203

Chain	Residue
B	GLU27
B	ASP59
B	HIS62
B	HIS80
B	HIS104
B	LYS108
B	THR129
B	GLN133
B	ARG158
B	FE201

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE D 201

Chain	Residue
D	ASP59
D	HIS80
D	HIS104
D	FE202
D	ODV203

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE D 202

Chain	Residue
D	HIS34
D	HIS58
D	ASP59
D	ASP161
D	FE201

---

site_id	AC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ODV D 203

Chain	Residue
D	GLU27
D	ASP59
D	HIS62
D	HIS80
D	HIS104
D	LYS108
D	SER126
D	THR129
D	GLN133
D	ARG158
D	FE201

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE E 201

Chain	Residue
E	ASP59
E	HIS80
E	HIS104
E	ODV203

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE E 202

Chain	Residue
E	HIS34
E	HIS58
E	ASP59
E	ASP161

---

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ODV E 203

Chain	Residue
E	GLU27
E	ASP59
E	HIS62
E	HIS80
E	HIS104
E	LYS108
E	SER126
E	THR129
E	GLN133
E	ARG158
E	FE201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:24706911, ECO:0007744|PDB:4MLM, ECO:0007744|PDB:4MLN

Chain	Residue	Details
A	TYR24
B	TYR24
D	TYR24
E	TYR24

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:24198335, ECO:0007744|PDB:4N71

Chain	Residue	Details
A	GLU27
B	GLU27
D	GLU27
E	GLU27

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	BINDING: BINDING => ECO:0000269|PubMed:24198335, ECO:0000269|PubMed:24706911, ECO:0007744|PDB:4MLM, ECO:0007744|PDB:4MLN, ECO:0007744|PDB:4N6W, ECO:0007744|PDB:4N71

Chain	Residue	Details
A	HIS34
A	ASP161
B	HIS34
B	HIS58
B	ASP59
B	HIS62
B	HIS80
B	HIS104
B	LYS108
B	SER126
B	ARG158
A	HIS58
B	ASP161
D	HIS34
D	HIS58
D	ASP59
D	HIS62
D	HIS80
D	HIS104
D	LYS108
D	SER126
D	ARG158
A	ASP59
D	ASP161
E	HIS34
E	HIS58
E	ASP59
E	HIS62
E	HIS80
E	HIS104
E	LYS108
E	SER126
E	ARG158
A	HIS62
E	ASP161
A	HIS80
A	HIS104
A	LYS108
A	SER126
A	ARG158

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Important for stereospecificity with the R-enantiomer => ECO:0000269|PubMed:24706911

Chain	Residue	Details
A	GLU27
B	GLU27
D	GLU27
E	GLU27

---