4N31

Structure and activity of Streptococcus pyogenes SipA: a signal peptidase homologue essential for pilus polymerisation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005886	cellular_component	plasma membrane
A	0006465	biological_process	signal peptide processing
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008236	molecular_function	serine-type peptidase activity
A	0009003	molecular_function	signal peptidase activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005886	cellular_component	plasma membrane
B	0006465	biological_process	signal peptide processing
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008236	molecular_function	serine-type peptidase activity
B	0009003	molecular_function	signal peptidase activity
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 A 201

Chain	Residue
A	ARG171
A	ARG171
A	GLY172
B	LYS163

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PTY B 201

Chain	Residue
B	ILE43
B	GLY56
B	LEU168
B	VAL170
B	ARG171
B	PO4202
B	HOH318
A	PHE39
A	VAL41
A	TYR62
A	LYS163
A	HOH333

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 B 202

Chain	Residue
A	VAL170
B	LEU60
B	THR166
B	PTY201

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