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4N2Y

Crystal structure of orotidine 5'-monophosphate decarboxylase from Archaeoglobus fulgidus

Functional Information from GO Data
ChainGOidnamespacecontents
A0004590molecular_functionorotidine-5'-phosphate decarboxylase activity
A0005829cellular_componentcytosol
A0006207biological_process'de novo' pyrimidine nucleobase biosynthetic process
A0006221biological_processpyrimidine nucleotide biosynthetic process
A0016831molecular_functioncarboxy-lyase activity
A0044205biological_process'de novo' UMP biosynthetic process
B0004590molecular_functionorotidine-5'-phosphate decarboxylase activity
B0005829cellular_componentcytosol
B0006207biological_process'de novo' pyrimidine nucleobase biosynthetic process
B0006221biological_processpyrimidine nucleotide biosynthetic process
B0016831molecular_functioncarboxy-lyase activity
B0044205biological_process'de novo' UMP biosynthetic process
C0004590molecular_functionorotidine-5'-phosphate decarboxylase activity
C0005829cellular_componentcytosol
C0006207biological_process'de novo' pyrimidine nucleobase biosynthetic process
C0006221biological_processpyrimidine nucleotide biosynthetic process
C0016831molecular_functioncarboxy-lyase activity
C0044205biological_process'de novo' UMP biosynthetic process
D0004590molecular_functionorotidine-5'-phosphate decarboxylase activity
D0005829cellular_componentcytosol
D0006207biological_process'de novo' pyrimidine nucleobase biosynthetic process
D0006221biological_processpyrimidine nucleotide biosynthetic process
D0016831molecular_functioncarboxy-lyase activity
D0044205biological_process'de novo' UMP biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE GOL A 301
ChainResidue
ALYS51
AASP77
ALYS79
APRO186
AHOH401
AHOH459
AHOH460
BASP82

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01200
ChainResidueDetails
ALYS79
BLYS79
CLYS79
DLYS79

site_idSWS_FT_FI2
Number of Residues28
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01200
ChainResidueDetails
AASP29
BASP77
BSER134
BPRO186
BGLY207
BARG208
CASP29
CLYS51
CASP77
CSER134
CPRO186
ALYS51
CGLY207
CARG208
DASP29
DLYS51
DASP77
DSER134
DPRO186
DGLY207
DARG208
AASP77
ASER134
APRO186
AGLY207
AARG208
BASP29
BLYS51

226707

PDB entries from 2024-10-30

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