4N0H

Crystal structure of S. cerevisiae mitochondrial GatFAB

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0006412	biological_process	translation
A	0007029	biological_process	endoplasmic reticulum organization
A	0016874	molecular_function	ligase activity
A	0030956	cellular_component	glutamyl-tRNA(Gln) amidotransferase complex
A	0032543	biological_process	mitochondrial translation
A	0050567	molecular_function	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
A	0070681	biological_process	glutaminyl-tRNAGln biosynthesis via transamidation
B	0003824	molecular_function	catalytic activity
B	0016874	molecular_function	ligase activity
B	0016884	molecular_function	carbon-nitrogen ligase activity, with glutamine as amido-N-donor
F	0005739	cellular_component	mitochondrion
F	0030956	cellular_component	glutamyl-tRNA(Gln) amidotransferase complex
F	0050567	molecular_function	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
F	0070681	biological_process	glutaminyl-tRNAGln biosynthesis via transamidation

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE NO3 A 501

Chain	Residue
A	ARG233
A	HOH641
F	LEU46
A	PHE243
A	SER244
A	MET248
A	PHE252
A	HIS253
A	TYR256
A	PRO391
A	HOH632

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Functional Information from PROSITE/UniProt

site_id	PS00571
Number of Residues	32
Details	AMIDASES Amidases signature. GGSSSGaAAsVAcdlvdfAlGtDtGgSVRlPA

Chain	Residue	Details
A	GLY128-ALA159

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site_id	PS01234
Number of Residues	15
Details	GATB Glutamyl-tRNA(Gln) amidotransferase subunit B signature. LNRsnvPLIELvTkP

Chain	Residue	Details
B	LEU177-PRO191

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Charge relay system => ECO:0000255|HAMAP-Rule:MF_03150

Chain	Residue	Details
A	LYS52
A	SER130

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000255|HAMAP-Rule:MF_03150

Chain	Residue	Details
A	SER154

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