Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0003938 | molecular_function | IMP dehydrogenase activity |
| C | 0006164 | biological_process | purine nucleotide biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0003938 | molecular_function | IMP dehydrogenase activity |
| D | 0006164 | biological_process | purine nucleotide biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE IMP A 501 |
| Chain | Residue |
| A | ALA46 |
| A | GLY336 |
| A | MET355 |
| A | GLY357 |
| A | SER358 |
| A | TYR381 |
| A | GLY383 |
| A | MET384 |
| A | GLY385 |
| A | GLU411 |
| A | GLY412 |
| A | MET48 |
| A | C91502 |
| A | HOH610 |
| A | HOH625 |
| A | HOH646 |
| A | HOH680 |
| A | HOH681 |
| A | ASN273 |
| A | GLY298 |
| A | SER299 |
| A | ILE300 |
| A | CYS301 |
| A | ASP334 |
| A | GLY335 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE C91 A 502 |
| Chain | Residue |
| A | ALA246 |
| A | THR303 |
| A | MET384 |
| A | GLY385 |
| A | MET390 |
| A | LEU408 |
| A | GLU411 |
| A | IMP501 |
| B | GLY439 |
| B | TYR440 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | TYR378 |
| A | ARG416 |
| A | HOH695 |
| B | THR472 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 504 |
| Chain | Residue |
| A | SER422 |
| A | ARG424 |
| A | HOH635 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 505 |
| Chain | Residue |
| A | GLN226 |
| A | ARG229 |
| A | HOH668 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACY A 506 |
| Chain | Residue |
| A | ILE29 |
| A | ASN40 |
| A | ASP207 |
| A | ARG435 |
| A | HOH662 |
| A | HOH665 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 507 |
| Chain | Residue |
| A | ARG62 |
| A | SER88 |
| A | GLU89 |
| A | LYS210 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 508 |
| Chain | Residue |
| A | THR460 |
| A | THR460 |
| B | THR460 |
| B | THR460 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 2F2 A 509 |
| Chain | Residue |
| A | TYR373 |
| A | GLN374 |
| D | TYR373 |
| D | GLN374 |
| site_id | BC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE IMP B 501 |
| Chain | Residue |
| B | ALA46 |
| B | MET48 |
| B | ASN273 |
| B | GLY298 |
| B | SER299 |
| B | ILE300 |
| B | CYS301 |
| B | ASP334 |
| B | GLY335 |
| B | GLY336 |
| B | MET355 |
| B | GLY357 |
| B | SER358 |
| B | TYR381 |
| B | GLY383 |
| B | MET384 |
| B | GLY385 |
| B | GLU411 |
| B | GLY412 |
| B | C91502 |
| B | ACY506 |
| B | HOH615 |
| B | HOH623 |
| B | HOH627 |
| B | HOH685 |
| B | HOH689 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE C91 B 502 |
| Chain | Residue |
| B | ACY506 |
| B | EDO509 |
| A | SER436 |
| A | GLY439 |
| A | TYR440 |
| B | ALA246 |
| B | THR303 |
| B | GLY385 |
| B | MET390 |
| B | LEU408 |
| B | GLU411 |
| B | IMP501 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 503 |
| Chain | Residue |
| A | THR472 |
| B | TYR378 |
| B | ARG416 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 504 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 505 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY B 506 |
| Chain | Residue |
| B | ASP244 |
| B | SER245 |
| B | ASN273 |
| B | IMP501 |
| B | C91502 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 507 |
| Chain | Residue |
| B | PHE371 |
| B | TYR373 |
| B | ARG416 |
| C | TYR373 |
| C | ARG416 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 508 |
| Chain | Residue |
| B | TYR373 |
| B | GLN374 |
| B | ARG416 |
| C | TYR373 |
| C | GLN374 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 509 |
| Chain | Residue |
| B | SER245 |
| B | ALA246 |
| B | C91502 |
| B | HOH620 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B 510 |
| Chain | Residue |
| B | GLN226 |
| B | ARG229 |
| B | HOH672 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 511 |
| Chain | Residue |
| B | SER422 |
| B | ARG424 |
| B | HOH622 |
| site_id | CC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE IMP C 501 |
| Chain | Residue |
| C | ALA46 |
| C | MET48 |
| C | ASN273 |
| C | GLY298 |
| C | SER299 |
| C | ILE300 |
| C | CYS301 |
| C | ASP334 |
| C | GLY335 |
| C | GLY336 |
| C | MET355 |
| C | GLY357 |
| C | SER358 |
| C | TYR381 |
| C | GLY383 |
| C | MET384 |
| C | GLY385 |
| C | GLU411 |
| C | GLY412 |
| C | C91502 |
| C | HOH610 |
| C | HOH623 |
| C | HOH630 |
| C | HOH643 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE C91 C 502 |
| Chain | Residue |
| C | ALA246 |
| C | HIS247 |
| C | MET390 |
| C | GLU411 |
| C | IMP501 |
| D | PRO24 |
| D | GLY439 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 503 |
| Chain | Residue |
| C | ARG376 |
| C | TYR378 |
| C | ARG416 |
| D | THR472 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 504 |
| site_id | CC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 505 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 506 |
| Chain | Residue |
| C | SER422 |
| C | ARG424 |
| C | HOH642 |
| C | HOH646 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 507 |
| Chain | Residue |
| C | THR460 |
| C | THR460 |
| D | THR460 |
| site_id | DC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE IMP D 501 |
| Chain | Residue |
| D | ALA46 |
| D | MET48 |
| D | GLY298 |
| D | SER299 |
| D | ILE300 |
| D | CYS301 |
| D | ASP334 |
| D | GLY335 |
| D | GLY336 |
| D | GLY357 |
| D | SER358 |
| D | TYR381 |
| D | GLY383 |
| D | MET384 |
| D | GLY385 |
| D | GLU411 |
| D | GLY412 |
| D | C91502 |
| D | HOH604 |
| site_id | DC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE C91 D 502 |
| Chain | Residue |
| C | GLY439 |
| C | TYR440 |
| D | ALA246 |
| D | THR303 |
| D | GLY385 |
| D | MET390 |
| D | GLU411 |
| D | IMP501 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 503 |
| Chain | Residue |
| C | THR472 |
| D | TYR378 |
| D | ARG416 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL D 504 |
| Chain | Residue |
| D | SER422 |
| D | ARG424 |
| D | SER425 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT |
| Chain | Residue | Details |
| A | VAL291-THR303 | |
