4MYH

Structure of the Glutathione bound mitochondrial ABC transporter, Atm1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0055085	biological_process	transmembrane transport
A	0140359	molecular_function	ABC-type transporter activity
B	0005524	molecular_function	ATP binding
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0055085	biological_process	transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity
C	0005524	molecular_function	ATP binding
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
C	0055085	biological_process	transmembrane transport
C	0140359	molecular_function	ABC-type transporter activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GSH B 701

Chain	Residue
B	ARG280
B	ARG284
B	ASN343
B	ASN390
B	SER394

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Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. ISGGEKQRLAIARVL

Chain	Residue	Details
A	ILE573-LEU587

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	378
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	VAL111-PHE132
A	LEU156-PHE179
A	LEU229-TYR252
A	PHE254-ILE274
A	PHE341-TYR359
A	LEU375-TYR396
C	VAL111-PHE132
C	LEU156-PHE179
C	LEU229-TYR252
C	PHE254-ILE274
C	PHE341-TYR359
C	LEU375-TYR396
B	VAL111-PHE132
B	LEU156-PHE179
B	LEU229-TYR252
B	PHE254-ILE274
B	PHE341-TYR359
B	LEU375-TYR396

---

site_id	SWS_FT_FI2
Number of Residues	111
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000269|PubMed:24604199, ECO:0000269|PubMed:25006243

Chain	Residue	Details
A	LYS133-GLY155
A	MET360-ASP374
C	LYS133-GLY155
C	MET360-ASP374
B	LYS133-GLY155
B	MET360-ASP374
A	GLN253
C	GLN253
B	GLN253

---

site_id	SWS_FT_FI3
Number of Residues	1218
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000269|PubMed:24604199, ECO:0000269|PubMed:25006243

Chain	Residue	Details
A	ALA180-VAL228
A	LYS275-ALA340
A	ARG397-LEU690
C	ALA180-VAL228
C	LYS275-ALA340
C	ARG397-LEU690
B	ALA180-VAL228
B	LYS275-ALA340
B	ARG397-LEU690

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:24604199, ECO:0007744|PDB:4MYH

Chain	Residue	Details
C	ASN343
B	ARG280
B	ASN343
A	ARG280
A	ASN343
C	ARG280

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q2G506

Chain	Residue	Details
A	GLY393
C	GLY393
B	GLY393

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site_id	SWS_FT_FI6
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9NP58

Chain	Residue	Details
A	TYR445
C	TYR445
B	TYR445

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site_id	SWS_FT_FI7
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434

Chain	Residue	Details
A	GLY469
C	GLY469
B	GLY469

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