Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006508 | biological_process | proteolysis |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0006508 | biological_process | proteolysis |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0006508 | biological_process | proteolysis |
| D | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE I1S A 301 |
| Chain | Residue |
| A | HIS39 |
| A | GLY174 |
| A | ASN181 |
| A | HOH443 |
| A | HOH516 |
| A | HOH553 |
| A | HOH598 |
| C | LYS76 |
| A | ALA149 |
| A | GLN150 |
| A | PRO151 |
| A | SER154 |
| A | TYR170 |
| A | ALA171 |
| A | GLY172 |
| A | SER173 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE I1S B 301 |
| Chain | Residue |
| B | HIS39 |
| B | ALA149 |
| B | GLN150 |
| B | PRO151 |
| B | SER154 |
| B | TYR170 |
| B | ALA171 |
| B | GLY172 |
| B | GLY174 |
| B | LYS175 |
| B | HOH402 |
| B | HOH411 |
| B | HOH432 |
| B | HOH473 |
| D | LYS76 |
| D | GLU77 |
| D | HOH440 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE I1S C 301 |
| Chain | Residue |
| A | LYS76 |
| A | GLU77 |
| A | HOH456 |
| A | HOH596 |
| C | HIS39 |
| C | ALA149 |
| C | GLN150 |
| C | PRO151 |
| C | SER154 |
| C | TYR170 |
| C | ALA171 |
| C | GLY172 |
| C | GLY174 |
| C | LYS175 |
| C | SER178 |
| C | HOH403 |
| C | HOH456 |
| C | HOH464 |
| C | HOH498 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE I1S D 301 |
| Chain | Residue |
| B | LYS76 |
| D | GLN150 |
| D | PRO151 |
| D | SER154 |
| D | TYR170 |
| D | ALA171 |
| D | GLY172 |
| D | GLY174 |
| D | LYS175 |
| D | HOH406 |
| D | HOH411 |
| D | HOH469 |
| D | HOH506 |
| D | HOH550 |
Functional Information from PROSITE/UniProt
| site_id | PS00672 |
| Number of Residues | 15 |
| Details | V8_HIS Serine proteases, V8 family, histidine active site. TGVVVGknTIvTnkH |
| Chain | Residue | Details |
| A | THR25-HIS39 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS39 | |
| D | HIS39 | |
| D | ASP78 | |
| D | SER154 | |
| A | ASP78 | |
| A | SER154 | |
| B | HIS39 | |
| B | ASP78 | |
| B | SER154 | |
| C | HIS39 | |
| C | ASP78 | |
| C | SER154 | |
