4MTS
Ni- and Zn-bound GloA2 at high resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004462 | molecular_function | lactoylglutathione lyase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019243 | biological_process | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004462 | molecular_function | lactoylglutathione lyase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019243 | biological_process | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 201 |
| Chain | Residue |
| A | HIS74 |
| A | GLU122 |
| A | NI203 |
| A | HOH370 |
| B | HIS5 |
| B | GLU56 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 202 |
| Chain | Residue |
| A | ASP33 |
| A | TYR34 |
| A | TYR34 |
| A | ARG32 |
| A | ARG32 |
| A | ASP33 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 203 |
| Chain | Residue |
| A | HIS74 |
| A | GLU122 |
| A | GOL201 |
| B | HIS5 |
| B | GLU56 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 201 |
| Chain | Residue |
| A | HIS5 |
| A | GLU56 |
| A | HOH301 |
| B | HIS74 |
| B | GLU122 |
| B | ZN202 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 202 |
| Chain | Residue |
| A | HOH301 |
| B | HIS105 |
| B | GLU122 |
| B | ZN201 |
| B | HOH301 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 203 |
| Chain | Residue |
| A | HOH331 |
| B | ARG9 |
| B | PHE39 |
| B | ASN60 |
| B | HOH414 |
| B | HOH435 |
