4MSO
X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006545 | biological_process | glycine biosynthetic process |
A | 0006730 | biological_process | one-carbon metabolic process |
A | 0008652 | biological_process | amino acid biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0019264 | biological_process | glycine biosynthetic process from serine |
A | 0030170 | molecular_function | pyridoxal phosphate binding |
A | 0035999 | biological_process | tetrahydrofolate interconversion |
B | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006545 | biological_process | glycine biosynthetic process |
B | 0006730 | biological_process | one-carbon metabolic process |
B | 0008652 | biological_process | amino acid biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0019264 | biological_process | glycine biosynthetic process from serine |
B | 0030170 | molecular_function | pyridoxal phosphate binding |
B | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE PO4 A 501 |
Chain | Residue |
A | GLY99 |
B | HOH886 |
A | SER100 |
A | THR227 |
A | HIS229 |
A | LYS230 |
A | HOH748 |
A | HOH858 |
B | GLY260 |
B | GLY261 |
site_id | AC2 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE PO4 A 502 |
Chain | Residue |
A | SER137 |
A | LYS139 |
A | HOH669 |
A | HOH765 |
A | HOH883 |
B | SER252 |
B | ALA253 |
B | ILE254 |
B | PHE255 |
B | ILE258 |
B | HOH686 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO B 501 |
Chain | Residue |
B | PRO42 |
B | THR369 |
B | ARG370 |
B | VAL413 |
B | TYR414 |
B | HOH729 |
B | HOH751 |
B | HOH829 |
site_id | AC4 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE PO4 B 502 |
Chain | Residue |
A | GLY260 |
A | GLY261 |
A | HOH636 |
B | SER98 |
B | GLY99 |
B | SER100 |
B | THR227 |
B | HIS229 |
B | LYS230 |
B | HOH674 |
B | HOH711 |
B | HOH961 |
Functional Information from PROSITE/UniProt
site_id | PS00096 |
Number of Residues | 17 |
Details | SHMT Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. DFvTTTTHKSLrGPRGG |
Chain | Residue | Details |
A | ASP222-GLY238 |