4MS7
Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| A | 0061578 | molecular_function | K63-linked deubiquitinase activity |
| A | 0070536 | biological_process | protein K63-linked deubiquitination |
| A | 0140492 | molecular_function | metal-dependent deubiquitinase activity |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0016579 | biological_process | protein deubiquitination |
| B | 0061578 | molecular_function | K63-linked deubiquitinase activity |
| B | 0070536 | biological_process | protein K63-linked deubiquitination |
| B | 0140492 | molecular_function | metal-dependent deubiquitinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 501 |
| Chain | Residue |
| A | HIS341 |
| A | HIS343 |
| A | ASP354 |
| A | HOH713 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 502 |
| Chain | Residue |
| A | HIS356 |
| A | CYS397 |
| A | HIS404 |
| A | HIS406 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 503 |
| Chain | Residue |
| A | HOH602 |
| A | THR254 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 504 |
| Chain | Residue |
| A | GLU286 |
| A | THR316 |
| A | CYS317 |
| A | VAL353 |
| A | ASP354 |
| A | THR357 |
| A | HOH713 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 505 |
| Chain | Residue |
| A | CYS317 |
| A | GLY318 |
| A | THR319 |
| A | TYR361 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 506 |
| Chain | Residue |
| A | PHE403 |
| A | HIS404 |
| A | HOH616 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TRS A 507 |
| Chain | Residue |
| A | LYS249 |
| A | HIS251 |
| A | ARG261 |
| A | THR262 |
| A | ASN298 |
| A | HOH613 |
| A | HOH637 |
| A | HOH659 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 501 |
| Chain | Residue |
| B | HIS356 |
| B | CYS397 |
| B | HIS404 |
| B | HIS406 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 502 |
| Chain | Residue |
| B | HIS341 |
| B | HIS343 |
| B | ASP354 |
| B | HOH715 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 503 |
| Chain | Residue |
| B | GLU286 |
| B | THR316 |
| B | CYS317 |
| B | TRP339 |
| B | VAL353 |
| B | ASP354 |
| B | THR357 |
| B | HOH715 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 504 |
| Chain | Residue |
| B | GLY318 |
| B | THR319 |
| B | TYR361 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 260 |
| Details | Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 26 |
| Details | Motif: {"description":"JAMM motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Indirect zinc-binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
