Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004418 | molecular_function | hydroxymethylbilane synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018160 | biological_process | peptidyl-pyrromethane cofactor linkage |
| A | 0033014 | biological_process | tetrapyrrole biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE DPM A 401 |
| Chain | Residue |
| A | SER79 |
| A | ALA168 |
| A | ALA194 |
| A | GLN197 |
| A | GLY198 |
| A | CYS241 |
| A | HOH506 |
| A | HOH544 |
| A | HOH559 |
| A | HOH565 |
| A | LYS81 |
| A | ASP82 |
| A | THR125 |
| A | SER126 |
| A | SER127 |
| A | ARG129 |
| A | ARG130 |
| A | ARG153 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 29P A 402 |
| Chain | Residue |
| A | ARG9 |
| A | SER11 |
| A | LEU13 |
| A | LYS81 |
| A | ASP82 |
| A | THR125 |
| A | SER126 |
| A | SER127 |
| A | ARG129 |
| A | ARG130 |
| A | ARG147 |
| A | GLY148 |
| A | ASN149 |
| A | ILE150 |
| A | ARG153 |
| A | ALA194 |
| A | CYS241 |
| A | HOH618 |
| A | HOH801 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 403 |
| Chain | Residue |
| A | PHE34 |
| A | GLU35 |
| A | ILE36 |
| A | ARG303 |
| A | HOH790 |
Functional Information from PROSITE/UniProt
| site_id | PS00533 |
| Number of Residues | 17 |
| Details | PORPHOBILINOGEN_DEAM Porphobilinogen deaminase cofactor-binding site. ERvFlkeMeGGCqVPIA |
| Chain | Residue | Details |
| A | GLU230-ALA246 | |
