Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4ML0

Crystal structure of E.coli DinJ-YafQ complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
A	0003677	molecular_function	DNA binding
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0015643	molecular_function	toxic substance binding
A	0043565	molecular_function	sequence-specific DNA binding
A	0044010	biological_process	single-species biofilm formation
B	0003677	molecular_function	DNA binding
B	0003723	molecular_function	RNA binding
B	0004519	molecular_function	endonuclease activity
B	0004521	molecular_function	RNA endonuclease activity
B	0006402	biological_process	mRNA catabolic process
B	0006415	biological_process	translational termination
C	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
C	0003677	molecular_function	DNA binding
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0015643	molecular_function	toxic substance binding
C	0043565	molecular_function	sequence-specific DNA binding
C	0044010	biological_process	single-species biofilm formation
D	0003677	molecular_function	DNA binding
D	0003723	molecular_function	RNA binding
D	0004519	molecular_function	endonuclease activity
D	0004521	molecular_function	RNA endonuclease activity
D	0006402	biological_process	mRNA catabolic process
D	0006415	biological_process	translational termination
E	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
E	0003677	molecular_function	DNA binding
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0015643	molecular_function	toxic substance binding
E	0043565	molecular_function	sequence-specific DNA binding
E	0044010	biological_process	single-species biofilm formation
F	0003677	molecular_function	DNA binding
F	0003723	molecular_function	RNA binding
F	0004519	molecular_function	endonuclease activity
F	0004521	molecular_function	RNA endonuclease activity
F	0006402	biological_process	mRNA catabolic process
F	0006415	biological_process	translational termination
G	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
G	0003677	molecular_function	DNA binding
G	0006351	biological_process	DNA-templated transcription
G	0006355	biological_process	regulation of DNA-templated transcription
G	0015643	molecular_function	toxic substance binding
G	0043565	molecular_function	sequence-specific DNA binding
G	0044010	biological_process	single-species biofilm formation
H	0003677	molecular_function	DNA binding
H	0003723	molecular_function	RNA binding
H	0004519	molecular_function	endonuclease activity
H	0004521	molecular_function	RNA endonuclease activity
H	0006402	biological_process	mRNA catabolic process
H	0006415	biological_process	translational termination
I	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
I	0003677	molecular_function	DNA binding
I	0006351	biological_process	DNA-templated transcription
I	0006355	biological_process	regulation of DNA-templated transcription
I	0015643	molecular_function	toxic substance binding
I	0043565	molecular_function	sequence-specific DNA binding
I	0044010	biological_process	single-species biofilm formation
J	0003677	molecular_function	DNA binding
J	0003723	molecular_function	RNA binding
J	0004519	molecular_function	endonuclease activity
J	0004521	molecular_function	RNA endonuclease activity
J	0006402	biological_process	mRNA catabolic process
J	0006415	biological_process	translational termination
K	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
K	0003677	molecular_function	DNA binding
K	0006351	biological_process	DNA-templated transcription
K	0006355	biological_process	regulation of DNA-templated transcription
K	0015643	molecular_function	toxic substance binding
K	0043565	molecular_function	sequence-specific DNA binding
K	0044010	biological_process	single-species biofilm formation
L	0003677	molecular_function	DNA binding
L	0003723	molecular_function	RNA binding
L	0004519	molecular_function	endonuclease activity
L	0004521	molecular_function	RNA endonuclease activity
L	0006402	biological_process	mRNA catabolic process
L	0006415	biological_process	translational termination
M	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
M	0003677	molecular_function	DNA binding
M	0006351	biological_process	DNA-templated transcription
M	0006355	biological_process	regulation of DNA-templated transcription
M	0015643	molecular_function	toxic substance binding
M	0043565	molecular_function	sequence-specific DNA binding
M	0044010	biological_process	single-species biofilm formation
N	0003677	molecular_function	DNA binding
N	0003723	molecular_function	RNA binding
N	0004519	molecular_function	endonuclease activity
N	0004521	molecular_function	RNA endonuclease activity
N	0006402	biological_process	mRNA catabolic process
N	0006415	biological_process	translational termination
O	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
O	0003677	molecular_function	DNA binding
O	0006351	biological_process	DNA-templated transcription
O	0006355	biological_process	regulation of DNA-templated transcription
O	0015643	molecular_function	toxic substance binding
O	0043565	molecular_function	sequence-specific DNA binding
O	0044010	biological_process	single-species biofilm formation
P	0003677	molecular_function	DNA binding
P	0003723	molecular_function	RNA binding
P	0004519	molecular_function	endonuclease activity
P	0004521	molecular_function	RNA endonuclease activity
P	0006402	biological_process	mRNA catabolic process
P	0006415	biological_process	translational termination

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 101

Chain	Residue
A	ARG52
A	GLU53
A	HOH208
A	HOH220
C	ARG43
C	HOH210
E	LYS63

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 102

Chain	Residue
A	ARG8
A	HOH223
A	HOH257
A	HOH260
C	LYS16
E	HOH246
A	ALA5
A	PHE6

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 103

Chain	Residue
A	SER31
A	ARG35
C	ARG10

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 104

Chain	Residue
A	ASN55
A	GLN56
A	HOH220
A	HOH237
A	HOH266
A	HOH271
E	GLN56
E	HOH244

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 101

Chain	Residue
A	ASP50
A	HOH201
B	HIS50
B	ASP61
B	HIS63
B	HIS87
B	HOH202
B	HOH219

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 102

Chain	Residue
A	GLU66
B	LYS73
B	LEU78
B	ARG80
B	HOH207
B	HOH217
G	LYS45

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 103

Chain	Residue
B	ARG22
B	LYS24
B	HOH218
B	HOH239
B	HOH242

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 104

Chain	Residue
B	PRO51
B	ARG60
B	HOH209
B	HOH215
B	HOH238
B	HOH276
D	PRO51
D	ARG60

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C 101

Chain	Residue
A	ALA9
A	ARG10
C	SER31
C	ARG35
C	HOH205
H	THR86
H	ALA88

site_id	BC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 D 101

Chain	Residue
C	PHE49
C	ASP50
C	HOH261
D	HIS50
D	ASP61
D	HIS63
D	ILE69
D	HIS87
D	HOH201
D	HOH204

site_id	BC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 E 101

Chain	Residue
E	ALA5
E	PHE6
E	ARG8
E	HOH230
E	HOH233
E	HOH239
E	HOH248
G	LYS16

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 102

Chain	Residue
C	ARG8
C	ARG10
E	SER31
E	ARG35

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 103

Chain	Residue
A	GLN56
E	ASN55
E	GLN56
E	HOH214
E	HOH223

site_id	BC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 F 101

Chain	Residue
E	PHE49
E	ASP50
E	HOH201
F	HIS50
F	ASP61
F	HIS63
F	HIS87
F	HOH203
F	HOH214

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 F 102

Chain	Residue
F	ALA89
F	HOH202
F	HOH263
F	ARG22
F	THR86

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 F 103

Chain	Residue
A	HOH211
C	LYS45
E	GLU66
F	LYS73
F	LEU78
F	ARG80
F	HOH251

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 G 101

Chain	Residue
E	ALA9
E	ARG10
G	SER31
G	ARG35
G	HOH216
G	HOH222
J	THR86
J	ALA88

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 G 102

Chain	Residue
A	GLN60
A	HOH280
G	ARG43
G	HOH207

site_id	CC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 H 101

Chain	Residue
F	PRO51
F	ARG60
H	PRO51
H	ARG60
H	HOH201
H	HOH204
H	HOH211
H	HOH214

site_id	CC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 H 102

Chain	Residue
G	ASP50
G	HOH206
G	HOH260
H	HIS50
H	ASP61
H	HIS63
H	ILE69
H	HIS87
H	HOH223

site_id	CC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE SO4 I 101

Chain	Residue
I	SER31
I	ARG35
I	HOH217
I	HOH218
I	HOH225
I	HOH240
I	HOH248
K	ARG8
K	ALA9
K	ARG10
P	ARG22
P	THR86
P	ALA88
P	ALA89

site_id	CC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 J 101

Chain	Residue
I	ASP50
I	HOH260
J	HIS50
J	ASP61
J	HIS63
J	HIS87
J	PHE91
J	HOH201
J	HOH205

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 J 102

Chain	Residue
J	PRO44
J	ALA45
J	HOH267
P	PRO44
P	ALA45

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 K 101

Chain	Residue
G	ARG10
I	ARG10
K	SER31
K	ARG35

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 K 102

Chain	Residue
I	LYS16
K	ALA5
K	PHE6
K	ARG8
M	HOH234

site_id	CC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 K 103

Chain	Residue
I	ARG43
K	ARG52
K	GLU53
K	HOH217
K	HOH226
K	HOH232
M	LYS63

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 K 104

Chain	Residue
K	ASN55
K	GLN56
K	HOH228
M	GLN56

site_id	DC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 L 101

Chain	Residue
J	PRO51
J	ARG60
L	PRO51
L	ARG60
L	HOH208
L	HOH210
L	HOH241
L	HOH245

site_id	DC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 L 102

Chain	Residue
K	PHE49
K	ASP50
K	HOH289
L	HIS50
L	ASP61
L	HIS63
L	HIS87
L	HOH202
L	HOH212

site_id	DC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 L 103

Chain	Residue
K	GLU66
K	HOH201
L	LYS73
L	LEU78
L	ARG80
O	LYS45

site_id	DC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 L 104

Chain	Residue
L	ARG22
L	THR86
L	ALA89
L	HOH203
L	HOH239
L	HOH249

site_id	DC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 M 101

Chain	Residue
M	ALA5
M	PHE6
M	ARG8
M	HOH232
M	HOH248
M	HOH269
O	LYS16

site_id	DC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 M 102

Chain	Residue
K	LYS63
M	ARG52
M	GLU53
M	HOH212
M	HOH213
M	HOH237
O	ARG43

site_id	DC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 M 103

Chain	Residue
K	GLN56
K	HOH244
M	ASN55
M	GLN56
M	HOH213
M	HOH253
M	HOH257
M	HOH266

site_id	DC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 M 104

Chain	Residue
M	SER31
M	ARG35
M	HOH249
M	HOH260
O	ALA9
O	ARG10

site_id	DC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 N 101

Chain	Residue
M	PHE49
M	ASP50
M	HOH201
M	HOH290
N	HIS50
N	ASP61
N	HIS63
N	HIS87
N	HOH211

site_id	EC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 N 102

Chain	Residue
N	PRO51
N	ARG60
N	HOH205
N	HOH209
N	HOH223
N	HOH276
P	PRO51
P	ARG60

site_id	EC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 N 103

Chain	Residue
I	LYS45
M	GLU66
M	HOH218
N	LYS73
N	LEU78
N	ARG80
N	HOH287
N	HOH298

site_id	EC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 N 104

Chain	Residue
N	ARG22
N	LYS24
N	HOH214
N	HOH215
N	HOH246
N	HOH302

site_id	EC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 N 105

Chain	Residue
D	LYS14
D	HOH210
N	ARG22
N	THR86
N	ALA88
N	HOH226
N	HOH244

site_id	EC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SO4 O 101

Chain	Residue
D	THR86
D	ALA88
D	ALA89
M	ARG8
M	ALA9
M	ARG10
O	SER31
O	ARG35
O	HOH206
O	HOH208
O	HOH243

site_id	EC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 P 101

Chain	Residue
O	ASP50
O	HOH202
O	HOH214
P	HIS50
P	ASP61
P	HIS63
P	ILE69
P	HIS87
P	HOH202

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton donor => ECO:0000305

Chain	Residue	Details
B	HIS87
D	HIS87
F	HIS87
H	HIS87
J	HIS87
L	HIS87
N	HIS87
P	HIS87

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)