Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG A 1001 |
| Chain | Residue |
| A | TYR54 |
| A | GLY64 |
| A | CYS65 |
| A | ALA92 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG A 1002 |
| Chain | Residue |
| A | PRO89 |
| A | PHE91 |
| A | LEU180 |
| A | VAL181 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 1003 |
| Chain | Residue |
| A | HIS268 |
| A | HOH1312 |
| A | ASP266 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1004 |
| Chain | Residue |
| A | ASP68 |
| A | HOH1146 |
| A | HOH1225 |
| A | HOH1408 |
| A | HOH1422 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 1005 |
| Chain | Residue |
| A | SER262 |
| A | ASN265 |
| A | HOH1176 |
| A | HOH1201 |
| A | HOH1371 |
| B | ASN135 |
| B | ILE138 |
| B | HIS268 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 1006 |
| Chain | Residue |
| A | ASP48 |
| A | LYS221 |
| C | ASP48 |
| C | PHE49 |
| C | ASP52 |
| C | ACT1007 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG B 1001 |
| Chain | Residue |
| B | TYR54 |
| B | GLY64 |
| B | CYS65 |
| B | ALA92 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG B 1002 |
| Chain | Residue |
| B | PRO89 |
| B | PHE91 |
| B | LEU180 |
| B | VAL181 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1003 |
| Chain | Residue |
| B | ASP266 |
| B | HIS268 |
| B | ACT1005 |
| B | ACT1006 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 1004 |
| Chain | Residue |
| B | ASP68 |
| B | HOH1192 |
| B | HOH1244 |
| B | HOH1253 |
| B | HOH1347 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT B 1005 |
| Chain | Residue |
| A | TYR86 |
| A | THR187 |
| A | ARG208 |
| A | TYR264 |
| B | ASP266 |
| B | HIS268 |
| B | ZN1003 |
| B | ACT1006 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT B 1006 |
| Chain | Residue |
| A | TYR86 |
| A | ARG208 |
| A | TRP261 |
| B | ASP266 |
| B | PRO267 |
| B | HIS268 |
| B | ZN1003 |
| B | ACT1005 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 1007 |
| Chain | Residue |
| B | ASP48 |
| B | SER146 |
| B | LYS221 |
| D | PHE49 |
| D | ASP52 |
| D | ACT1006 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 1008 |
| Chain | Residue |
| B | ARG270 |
| B | HOH1159 |
| B | HOH1348 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG C 1001 |
| Chain | Residue |
| C | TYR54 |
| C | GLY64 |
| C | CYS65 |
| C | ALA92 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG C 1002 |
| Chain | Residue |
| C | PRO89 |
| C | PHE91 |
| C | LEU180 |
| C | VAL181 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1003 |
| Chain | Residue |
| C | ASP266 |
| C | HIS268 |
| C | ACT1005 |
| C | ACT1006 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 1004 |
| Chain | Residue |
| C | ASP68 |
| C | HOH1158 |
| C | HOH1198 |
| C | HOH1222 |
| C | HOH1368 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT C 1005 |
| Chain | Residue |
| C | ASP266 |
| C | PRO267 |
| C | HIS268 |
| C | ZN1003 |
| C | ACT1006 |
| D | TYR86 |
| D | ARG208 |
| D | TRP261 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT C 1006 |
| Chain | Residue |
| C | ZN1003 |
| C | ACT1005 |
| D | TYR86 |
| D | ARG208 |
| D | TYR264 |
| C | ASP266 |
| C | HIS268 |
| site_id | CC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT C 1007 |
| Chain | Residue |
| A | ASP48 |
| A | PHE49 |
| A | ASP52 |
| A | ACT1006 |
| C | ASP48 |
| C | LYS221 |
| C | HOH1300 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT C 1008 |
| Chain | Residue |
| C | ARG270 |
| C | HOH1329 |
| C | HOH1371 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT C 1009 |
| Chain | Residue |
| C | SER262 |
| C | ASN265 |
| C | ASP266 |
| C | ARG269 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG D 1001 |
| Chain | Residue |
| D | TYR54 |
| D | CYS65 |
| D | ALA92 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HG D 1002 |
| Chain | Residue |
| D | VAL67 |
| D | PRO89 |
| D | PHE91 |
| D | LEU180 |
| D | VAL181 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1003 |
| Chain | Residue |
| D | ASP266 |
| D | HIS268 |
| D | HOH1274 |
| D | HOH1384 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1004 |
| Chain | Residue |
| D | ASP68 |
| D | HOH1248 |
| D | HOH1352 |
| D | HOH1353 |
| site_id | DC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT D 1005 |
| Chain | Residue |
| C | ASN135 |
| C | ILE138 |
| C | HIS268 |
| C | HOH1166 |
| D | SER262 |
| D | ASN265 |
| D | HOH1171 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT D 1006 |
| Chain | Residue |
| B | ASP48 |
| B | PHE49 |
| B | ASP52 |
| B | ACT1007 |
| D | ASP48 |
| D | LYS221 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 272 |
| Details | Region: {"description":"Pore-forming domain","evidences":[{"source":"PubMed","id":"25847242","evidenceCode":"ECO:0000305"}]} |
