4MJR
E. coli sliding clamp in complex with (S)-Carprofen
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006260 | biological_process | DNA replication |
A | 0006261 | biological_process | DNA-templated DNA replication |
A | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
A | 0006974 | biological_process | DNA damage response |
A | 0008408 | molecular_function | 3'-5' exonuclease activity |
A | 0009360 | cellular_component | DNA polymerase III complex |
A | 0030174 | biological_process | regulation of DNA-templated DNA replication initiation |
A | 0030894 | cellular_component | replisome |
A | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
A | 0042276 | biological_process | error-prone translesion synthesis |
A | 0042802 | molecular_function | identical protein binding |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0044787 | biological_process | bacterial-type DNA replication |
A | 1990078 | cellular_component | replication inhibiting complex |
A | 1990085 | cellular_component | Hda-beta clamp complex |
B | 0003677 | molecular_function | DNA binding |
B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006260 | biological_process | DNA replication |
B | 0006261 | biological_process | DNA-templated DNA replication |
B | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
B | 0006974 | biological_process | DNA damage response |
B | 0008408 | molecular_function | 3'-5' exonuclease activity |
B | 0009360 | cellular_component | DNA polymerase III complex |
B | 0030174 | biological_process | regulation of DNA-templated DNA replication initiation |
B | 0030894 | cellular_component | replisome |
B | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
B | 0042276 | biological_process | error-prone translesion synthesis |
B | 0042802 | molecular_function | identical protein binding |
B | 0042803 | molecular_function | protein homodimerization activity |
B | 0044787 | biological_process | bacterial-type DNA replication |
B | 1990078 | cellular_component | replication inhibiting complex |
B | 1990085 | cellular_component | Hda-beta clamp complex |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PGE A 401 |
Chain | Residue |
A | PRO83 |
A | GLU84 |
A | GLY85 |
A | ALA86 |
A | GLU87 |
A | ARG100 |
A | SER101 |
A | GLY102 |
A | HOH541 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PEG A 402 |
Chain | Residue |
A | LYS277 |
B | HIS9 |
B | THR41 |
B | ARG56 |
B | VAL57 |
B | ALA58 |
B | ASP229 |
B | HOH745 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL A 403 |
Chain | Residue |
A | GLU6 |
A | HIS9 |
A | GLN61 |
A | HOH504 |
B | HOH527 |
site_id | AC4 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE 0LA A 404 |
Chain | Residue |
A | ARG152 |
A | TYR154 |
A | THR172 |
A | GLY174 |
A | ARG176 |
A | LEU177 |
A | VAL247 |
A | VAL360 |
A | MET362 |
B | HOH637 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE PEG B 401 |
Chain | Residue |
A | SER181 |
A | SER356 |
B | ARG365 |
B | HOH636 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE PEG B 402 |
Chain | Residue |
A | GLU6 |
A | GLU8 |
A | GLY85 |
A | GLU87 |
A | HOH756 |
A | HOH776 |
B | ASP120 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PGE B 403 |
Chain | Residue |
B | SER18 |
B | ARG73 |
B | PHE76 |
B | ARG80 |
B | HOH755 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE PEG B 404 |
Chain | Residue |
A | TRP122 |
A | GLN217 |
A | ARG224 |
A | HOH680 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CA B 405 |
Chain | Residue |
B | GLU334 |
B | ASN335 |
B | ASP351 |
B | ALA353 |
site_id | BC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 406 |
Chain | Residue |
B | ALA89 |
B | LEU98 |
B | ARG100 |
site_id | BC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL B 407 |
Chain | Residue |
A | PHE278 |
B | GLU6 |
B | GLN61 |
B | HOH608 |
B | HOH623 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000305|PubMed:18191219 |
Chain | Residue | Details |
A | ARG24 | |
A | GLN149 | |
A | TYR153 | |
B | ARG24 | |
B | GLN149 | |
B | TYR153 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:18191219 |
Chain | Residue | Details |
A | ARG73 | |
B | ARG73 |