4MH5

Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with (S)-glutamate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GLU A 301

Chain	Residue
A	TYR63
A	HOH408
A	HOH411
A	HOH412
A	HOH440
A	PRO90
A	LEU91
A	THR92
A	ARG97
A	GLY142
A	ALA143
A	THR144
A	GLU191

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE K A 302

Chain	Residue
A	ASN5
A	ASN5
A	SER52
A	SER52
A	HOH401
A	HOH401
A	HOH482
A	HOH482

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K A 303

Chain	Residue
A	SER24
A	ARG26
A	HOH448
A	HOH555
A	HOH669
A	HOH670

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 304

Chain	Residue
A	ARG33
A	LEU57

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 305

Chain	Residue
A	GLN239
A	ASP242
A	LEU244
A	HIS245

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 306

Chain	Residue
A	LYS99
A	THR109
A	HOH436
A	HOH558
A	HOH581
A	HOH608

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21907808","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3S9E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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