Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

4MDR

Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain D190A mutant, in complex with a sorting peptide from the amyloid precursor protein (APP)

Functional Information from GO Data
ChainGOidnamespacecontents
A0006886biological_processintracellular protein transport
A0016192biological_processvesicle-mediated transport
A0030131cellular_componentclathrin adaptor complex
Functional Information from PDB Data
site_idAC1
Number of Residues14
DetailsBINDING SITE FOR CHAIN B OF AMYLOID BETA A4 PROTEIN
ChainResidue
ASER254
APHE299
BHOH701
BHOH702
BHOH703
BHOH704
APHE255
AHIS256
ASER257
ALEU261
AGLU265
ATHR280
AARG283
AARG297

Functional Information from PROSITE/UniProt
site_idPS00991
Number of Residues15
DetailsCLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. LrLQPPqGeLtVmrY
ChainResidueDetails
ALEU270-TYR284

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P08592","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

245011

PDB entries from 2025-11-19

PDB statisticsPDBj update infoContact PDBjnumon