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4MBE

Sac3:Sus1:Cdc31:Nup1 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000226biological_processmicrotubule cytoskeleton organization
A0003674molecular_functionmolecular_function
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005635cellular_componentnuclear envelope
A0005737cellular_componentcytoplasm
A0005816cellular_componentspindle pole body
A0005825cellular_componenthalf bridge of spindle pole body
A0005856cellular_componentcytoskeleton
A0006406biological_processmRNA export from nucleus
A0008017molecular_functionmicrotubule binding
A0030474biological_processspindle pole body duplication
A0042802molecular_functionidentical protein binding
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0044732cellular_componentmitotic spindle pole body
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046872molecular_functionmetal ion binding
A0048193biological_processGolgi vesicle transport
A0051301biological_processcell division
A0070390cellular_componenttranscription export complex 2
C0000124cellular_componentSAGA complex
C0000932cellular_componentP-body
C0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
C0003682molecular_functionchromatin binding
C0003713molecular_functiontranscription coactivator activity
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005643cellular_componentnuclear pore
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0006325biological_processchromatin organization
C0006357biological_processregulation of transcription by RNA polymerase II
C0006368biological_processtranscription elongation by RNA polymerase II
C0006406biological_processmRNA export from nucleus
C0008047molecular_functionenzyme activator activity
C0015031biological_processprotein transport
C0016973biological_processpoly(A)+ mRNA export from nucleus
C0032880biological_processregulation of protein localization
C0045893biological_processpositive regulation of DNA-templated transcription
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0046695cellular_componentSLIK (SAGA-like) complex
C0051028biological_processmRNA transport
C0070390cellular_componenttranscription export complex 2
C0071028biological_processnuclear mRNA surveillance
C0071819cellular_componentDUBm complex
D0000226biological_processmicrotubule cytoskeleton organization
D0003674molecular_functionmolecular_function
D0005509molecular_functioncalcium ion binding
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005635cellular_componentnuclear envelope
D0005737cellular_componentcytoplasm
D0005816cellular_componentspindle pole body
D0005825cellular_componenthalf bridge of spindle pole body
D0005856cellular_componentcytoskeleton
D0006406biological_processmRNA export from nucleus
D0008017molecular_functionmicrotubule binding
D0030474biological_processspindle pole body duplication
D0042802molecular_functionidentical protein binding
D0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
D0044732cellular_componentmitotic spindle pole body
D0045944biological_processpositive regulation of transcription by RNA polymerase II
D0046872molecular_functionmetal ion binding
D0048193biological_processGolgi vesicle transport
D0051301biological_processcell division
D0070390cellular_componenttranscription export complex 2
F0000124cellular_componentSAGA complex
F0000932cellular_componentP-body
F0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
F0003682molecular_functionchromatin binding
F0003713molecular_functiontranscription coactivator activity
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005643cellular_componentnuclear pore
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0006325biological_processchromatin organization
F0006357biological_processregulation of transcription by RNA polymerase II
F0006368biological_processtranscription elongation by RNA polymerase II
F0006406biological_processmRNA export from nucleus
F0008047molecular_functionenzyme activator activity
F0015031biological_processprotein transport
F0016973biological_processpoly(A)+ mRNA export from nucleus
F0032880biological_processregulation of protein localization
F0045893biological_processpositive regulation of DNA-templated transcription
F0045944biological_processpositive regulation of transcription by RNA polymerase II
F0046695cellular_componentSLIK (SAGA-like) complex
F0051028biological_processmRNA transport
F0070390cellular_componenttranscription export complex 2
F0071028biological_processnuclear mRNA surveillance
F0071819cellular_componentDUBm complex
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A 201
ChainResidue
AASP33
AASN35
AASP37
APHE39
AHOH302

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A 202
ChainResidue
AGLU153
AASP142
AASP144
AASP146
AGLU148

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA D 201
ChainResidue
DASP142
DASP144
DASP146
DGLU148
DGLU153

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA D 202
ChainResidue
DASP33
DASN35
DASP37
DPHE39
DGLU44

Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DMNNDGFLDyhEL
ChainResidueDetails
AASP33-LEU45
AASP142-PHE154

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
CLYS68
DASP33
DASN35
DASP37
DGLU44
DASP142
DASP144
DASP146
DGLU148
DGLU153
AASN35
FLYS68
AGLU44
AASP142
AASP144
AASP146
AGLU148
AGLU153

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956
ChainResidueDetails
ATHR130
DTHR130

224931

PDB entries from 2024-09-11

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