Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4MBE

Sac3:Sus1:Cdc31:Nup1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000226	biological_process	microtubule cytoskeleton organization
A	0003674	molecular_function	molecular_function
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005635	cellular_component	nuclear envelope
A	0005816	cellular_component	spindle pole body
A	0005825	cellular_component	half bridge of spindle pole body
A	0006406	biological_process	mRNA export from nucleus
A	0008017	molecular_function	microtubule binding
A	0030474	biological_process	spindle pole body duplication
A	0042802	molecular_function	identical protein binding
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0044732	cellular_component	mitotic spindle pole body
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0046872	molecular_function	metal ion binding
A	0048193	biological_process	Golgi vesicle transport
A	0051301	biological_process	cell division
A	0070390	cellular_component	transcription export complex 2
C	0000124	cellular_component	SAGA complex
C	0000932	cellular_component	P-body
C	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
C	0003682	molecular_function	chromatin binding
C	0003713	molecular_function	transcription coactivator activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005643	cellular_component	nuclear pore
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0006325	biological_process	chromatin organization
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0006368	biological_process	transcription elongation by RNA polymerase II
C	0006406	biological_process	mRNA export from nucleus
C	0008047	molecular_function	enzyme activator activity
C	0015031	biological_process	protein transport
C	0016973	biological_process	poly(A)+ mRNA export from nucleus
C	0032880	biological_process	regulation of protein localization
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0046695	cellular_component	SLIK (SAGA-like) complex
C	0051028	biological_process	mRNA transport
C	0070390	cellular_component	transcription export complex 2
C	0071028	biological_process	nuclear mRNA surveillance
C	0071819	cellular_component	DUBm complex
D	0000226	biological_process	microtubule cytoskeleton organization
D	0003674	molecular_function	molecular_function
D	0005509	molecular_function	calcium ion binding
D	0005515	molecular_function	protein binding
D	0005635	cellular_component	nuclear envelope
D	0005816	cellular_component	spindle pole body
D	0005825	cellular_component	half bridge of spindle pole body
D	0006406	biological_process	mRNA export from nucleus
D	0008017	molecular_function	microtubule binding
D	0030474	biological_process	spindle pole body duplication
D	0042802	molecular_function	identical protein binding
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0044732	cellular_component	mitotic spindle pole body
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0046872	molecular_function	metal ion binding
D	0048193	biological_process	Golgi vesicle transport
D	0051301	biological_process	cell division
D	0070390	cellular_component	transcription export complex 2
F	0000124	cellular_component	SAGA complex
F	0000932	cellular_component	P-body
F	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
F	0003682	molecular_function	chromatin binding
F	0003713	molecular_function	transcription coactivator activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005643	cellular_component	nuclear pore
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0006325	biological_process	chromatin organization
F	0006357	biological_process	regulation of transcription by RNA polymerase II
F	0006368	biological_process	transcription elongation by RNA polymerase II
F	0006406	biological_process	mRNA export from nucleus
F	0008047	molecular_function	enzyme activator activity
F	0015031	biological_process	protein transport
F	0016973	biological_process	poly(A)+ mRNA export from nucleus
F	0032880	biological_process	regulation of protein localization
F	0045893	biological_process	positive regulation of DNA-templated transcription
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0046695	cellular_component	SLIK (SAGA-like) complex
F	0051028	biological_process	mRNA transport
F	0070390	cellular_component	transcription export complex 2
F	0071028	biological_process	nuclear mRNA surveillance
F	0071819	cellular_component	DUBm complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 201

Chain	Residue
A	ASP33
A	ASN35
A	ASP37
A	PHE39
A	HOH302

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 202

Chain	Residue
A	GLU153
A	ASP142
A	ASP144
A	ASP146
A	GLU148

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 201

Chain	Residue
D	ASP142
D	ASP144
D	ASP146
D	GLU148
D	GLU153

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 202

Chain	Residue
D	ASP33
D	ASN35
D	ASP37
D	PHE39
D	GLU44

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DMNNDGFLDyhEL

Chain	Residue	Details
A	ASP33-LEU45
A	ASP142-PHE154

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	70
Details	Domain: {"description":"EF-hand 2","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	70
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	64
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Repeat: {"description":"FXF 1"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)