4M9R
Crystal structure of CED-3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 13 |
| Details | CASPASE_HIS Caspase family histidine active site. Hgd..SaiLvILSHG |
| Chain | Residue | Details |
| A | HIS304-GLY316 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P29466 |
| Chain | Residue | Details |
| A | HIS315 | |
| B | HIS315 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:24065769, ECO:0000269|PubMed:8654923, ECO:0000269|PubMed:9857046 |
| Chain | Residue | Details |
| A | SER358 | |
| B | SER358 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:8654923 |
| Chain | Residue | Details |
| A | ASP221 | |
| A | ASP374 | |
| A | ASP388 | |
| B | ASP221 | |
| B | ASP374 | |
| B | ASP388 |
