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4M64

3D crystal structure of Na+/melibiose symporter of Salmonella typhimurium

Functional Information from GO Data
ChainGOidnamespacecontents
A0005886cellular_componentplasma membrane
A0006814biological_processsodium ion transport
A0008643biological_processcarbohydrate transport
A0015293molecular_functionsymporter activity
A0016020cellular_componentmembrane
A0022857molecular_functiontransmembrane transporter activity
A0055085biological_processtransmembrane transport
B0005886cellular_componentplasma membrane
B0006814biological_processsodium ion transport
B0008643biological_processcarbohydrate transport
B0015293molecular_functionsymporter activity
B0016020cellular_componentmembrane
B0022857molecular_functiontransmembrane transporter activity
B0055085biological_processtransmembrane transport
C0005886cellular_componentplasma membrane
C0006814biological_processsodium ion transport
C0008643biological_processcarbohydrate transport
C0015293molecular_functionsymporter activity
C0016020cellular_componentmembrane
C0022857molecular_functiontransmembrane transporter activity
C0055085biological_processtransmembrane transport
D0005886cellular_componentplasma membrane
D0006814biological_processsodium ion transport
D0008643biological_processcarbohydrate transport
D0015293molecular_functionsymporter activity
D0016020cellular_componentmembrane
D0022857molecular_functiontransmembrane transporter activity
D0055085biological_processtransmembrane transport
Functional Information from PROSITE/UniProt
site_idPS00872
Number of Residues26
DetailsNA_GALACTOSIDE_SYMP Sodium:galactoside symporter family signature. DpimGwivNatrsrw..GKFKPWILiGT
ChainResidueDetails
AASP59-THR84

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues500
DetailsTOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:34341464, ECO:0007744|PDB:7L16, ECO:0007744|PDB:7L17
ChainResidueDetails
AMET1-THR7
BLEU130-GLN143
BVAL201-GLN232
BVAL290-ARG296
BALA350-SER366
BTYR432-ALA476
CMET1-THR7
CASN67-PHE76
CLEU130-GLN143
CVAL201-GLN232
CVAL290-ARG296
AASN67-PHE76
CALA350-SER366
CTYR432-ALA476
DMET1-THR7
DASN67-PHE76
DLEU130-GLN143
DVAL201-GLN232
DVAL290-ARG296
DALA350-SER366
DTYR432-ALA476
ALEU130-GLN143
AVAL201-GLN232
AVAL290-ARG296
AALA350-SER366
ATYR432-ALA476
BMET1-THR7
BASN67-PHE76

site_idSWS_FT_FI2
Number of Residues1096
DetailsTRANSMEM: Helical => ECO:0000269|PubMed:34341464, ECO:0007744|PDB:7L16, ECO:0007744|PDB:7L17
ChainResidueDetails
ALYS8-MET30
AALA324-VAL349
AILE367-ILE394
AGLY409-ARG431
BLYS8-MET30
BGLY42-VAL66
BLYS77-ALA97
BGLN105-SER129
BLEU144-VAL167
BGLY178-ASN200
BLEU233-ILE255
AGLY42-VAL66
BLEU267-LEU289
BILE297-LEU318
BALA324-VAL349
BILE367-ILE394
BGLY409-ARG431
CLYS8-MET30
CGLY42-VAL66
CLYS77-ALA97
CGLN105-SER129
CLEU144-VAL167
ALYS77-ALA97
CGLY178-ASN200
CLEU233-ILE255
CLEU267-LEU289
CILE297-LEU318
CALA324-VAL349
CILE367-ILE394
CGLY409-ARG431
DLYS8-MET30
DGLY42-VAL66
DLYS77-ALA97
AGLN105-SER129
DGLN105-SER129
DLEU144-VAL167
DGLY178-ASN200
DLEU233-ILE255
DLEU267-LEU289
DILE297-LEU318
DALA324-VAL349
DILE367-ILE394
DGLY409-ARG431
ALEU144-VAL167
AGLY178-ASN200
ALEU233-ILE255
ALEU267-LEU289
AILE297-LEU318

site_idSWS_FT_FI3
Number of Residues208
DetailsTOPO_DOM: Periplasmic => ECO:0000269|PubMed:34341464, ECO:0007744|PDB:7L16, ECO:0007744|PDB:7L17
ChainResidueDetails
ATYR31-VAL41
BTYR256-ASP266
BALA319-ASN323
BGLY395-GLN408
CTYR31-VAL41
CHIS98-ALA104
CSER168-PHE177
CTYR256-ASP266
CALA319-ASN323
CGLY395-GLN408
DTYR31-VAL41
AHIS98-ALA104
DHIS98-ALA104
DSER168-PHE177
DTYR256-ASP266
DALA319-ASN323
DGLY395-GLN408
ASER168-PHE177
ATYR256-ASP266
AALA319-ASN323
AGLY395-GLN408
BTYR31-VAL41
BHIS98-ALA104
BSER168-PHE177

site_idSWS_FT_FI4
Number of Residues16
DetailsBINDING: BINDING => ECO:0000269|PubMed:34341464, ECO:0007744|PDB:7L17
ChainResidueDetails
ALYS18
CASP124
CTRP128
CARG149
DLYS18
DASP124
DTRP128
DARG149
AASP124
ATRP128
AARG149
BLYS18
BASP124
BTRP128
BARG149
CLYS18

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PDB entries from 2024-11-20

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