4M5S
Human alphaB crystallin core domain in complex with C-terminal peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SIN A 201 |
| Chain | Residue |
| A | HIS83 |
| A | HIS83 |
| A | ARG116 |
| A | ARG116 |
| site_id | AC2 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR CHAIN B OF ALPHA-CRYSTALLIN B CHAIN |
| Chain | Residue |
| A | LEU94 |
| A | LYS121 |
| A | PRO130 |
| A | LEU131 |
| A | ILE133 |
| A | SER135 |
| A | SER136 |
| A | LEU137 |
| A | SER138 |
| A | ARG149 |
| A | LYS150 |
| A | GLN151 |
| A | VAL152 |
| A | HOH305 |
| A | HOH307 |
| A | HOH332 |
| A | HOH342 |
| B | GLY155 |
| B | HOH201 |
| B | HOH202 |
| B | HOH203 |
| B | HOH204 |
| B | HOH205 |
| B | HOH206 |
| B | HOH207 |
| B | HOH208 |
| B | HOH209 |
| B | HOH210 |
| B | HOH212 |
| A | ARG69 |
| A | PRO86 |
| A | VAL91 |
| A | LYS92 |
| A | VAL93 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS83 | |
| A | GLU106 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:22890888 |
| Chain | Residue | Details |
| A | HIS104 | |
| A | HIS111 | |
| A | HIS119 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Susceptible to oxidation |
| Chain | Residue | Details |
| A | MET68 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine; partial => ECO:0000269|PubMed:11369851, ECO:0000269|PubMed:22120592 |
| Chain | Residue | Details |
| A | LYS92 |
