4M4R
Epha4 ectodomain complex with ephrin a5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005003 | molecular_function | ephrin receptor activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| A | 0016020 | cellular_component | membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0046875 | molecular_function | ephrin receptor binding |
| B | 0048013 | biological_process | ephrin receptor signaling pathway |
| C | 0005003 | molecular_function | ephrin receptor activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
| C | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| C | 0016020 | cellular_component | membrane |
| D | 0016020 | cellular_component | membrane |
| D | 0046875 | molecular_function | ephrin receptor binding |
| D | 0048013 | biological_process | ephrin receptor signaling pathway |
| E | 0005003 | molecular_function | ephrin receptor activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0006468 | biological_process | protein phosphorylation |
| E | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| E | 0016020 | cellular_component | membrane |
| F | 0016020 | cellular_component | membrane |
| F | 0046875 | molecular_function | ephrin receptor binding |
| F | 0048013 | biological_process | ephrin receptor signaling pathway |
| G | 0005003 | molecular_function | ephrin receptor activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0006468 | biological_process | protein phosphorylation |
| G | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| G | 0016020 | cellular_component | membrane |
| H | 0016020 | cellular_component | membrane |
| H | 0046875 | molecular_function | ephrin receptor binding |
| H | 0048013 | biological_process | ephrin receptor signaling pathway |
Functional Information from PROSITE/UniProt
| site_id | PS00790 |
| Number of Residues | 21 |
| Details | RECEPTOR_TYR_KIN_V_1 Receptor tyrosine kinase class V signature 1. FqDvGACIALVSVRVfykKCP |
| Chain | Residue | Details |
| A | PHE185-PRO205 |
| site_id | PS00791 |
| Number of Residues | 21 |
| Details | RECEPTOR_TYR_KIN_V_2 Receptor tyrosine kinase class V signature 2. CgaDGEWlv.PIGnClCnaGHE |
| Chain | Residue | Details |
| A | CYS247-GLU267 |
| site_id | PS01299 |
| Number of Residues | 28 |
| Details | EPHRIN_RBD_1 Ephrin receptor-binding (ephrin RBD) domain signature. KFSeKFQlFTPfslGfEFrpgreYFyiS |
| Chain | Residue | Details |
| B | LYS113-SER140 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 716 |
| Details | Domain: {"description":"Eph LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00883","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 444 |
| Details | Domain: {"description":"Fibronectin type-III 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 388 |
| Details | Domain: {"description":"Fibronectin type-III 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 532 |
| Details | Domain: {"description":"Ephrin RBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00884","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17400922","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
