4LWZ

Crystal structure of Myo5b globular tail domain in complex with inactive Rab11a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GDP A 201

Chain	Residue
A	GLY21
A	SER40
A	ASN124
A	LYS125
A	ASP127
A	LEU128
A	SER154
A	ALA155
A	LEU156
A	MG202
A	HOH302
A	VAL22
A	HOH307
A	HOH308
A	HOH317
A	GLY23
A	LYS24
A	SER25
A	ASN26
A	PHE36
A	ASN37
A	LEU38

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 202

Chain	Residue
A	SER25
A	THR43
A	GDP201
A	HOH302
A	HOH307
A	HOH308

---

site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GDP C 201

Chain	Residue
C	ASP19
C	GLY21
C	VAL22
C	GLY23
C	LYS24
C	SER25
C	ASN26
C	PHE36
C	ASN37
C	LEU38
C	SER40
C	ASN124
C	LYS125
C	ASP127
C	LEU128
C	SER154
C	ALA155
C	LEU156
C	MG202
C	HOH301
C	HOH315

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 202

Chain	Residue
C	SER25
C	THR43
C	GDP201
C	HOH301
C	HOH302

---

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL

Chain	Residue	Details
A	VAL14-LEU27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH

Chain	Residue	Details
A	SER20
C	SER20

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH, ECO:0007744|PDB:2HV8

Chain	Residue	Details
A	GLY21
A	ASP127
A	ALA155
A	LEU156
C	GLY21
C	GLY23
C	LYS24
C	ASN26
C	ASN37
C	LEU38
C	SER40
A	GLY23
C	GLY69
C	LYS125
C	ASP127
C	ALA155
C	LEU156
A	LYS24
A	ASN26
A	ASN37
A	LEU38
A	SER40
A	GLY69
A	LYS125

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0007744|PDB:2GZH

Chain	Residue	Details
A	VAL22
C	VAL22

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:15837192, ECO:0000269|PubMed:16034420, ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:1OIX, ECO:0007744|PDB:1YZK, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH, ECO:0007744|PDB:2HV8

Chain	Residue	Details
A	SER25
A	THR43
C	SER25
C	THR43

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH

Chain	Residue	Details
A	SER42
C	SER42

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD

Chain	Residue	Details
A	ASP66
C	ASP66

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH

Chain	Residue	Details
A	ASN124
C	ASN124

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: N-acetylglycine => ECO:0000269|Ref.11

Chain	Residue	Details
A	GLY2
C	GLY2

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32974215

Chain	Residue	Details
A	ARG4
C	ARG4

---