Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 601 |
| Chain | Residue |
| A | GLU490 |
| B | GLU524 |
| B | PTR527 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 602 |
| Chain | Residue |
| A | GLU524 |
| A | PTR527 |
| A | GLU529 |
| A | HOH726 |
| B | GLU490 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SK8 A 603 |
| Chain | Residue |
| A | VAL281 |
| A | ALA293 |
| A | LYS295 |
| A | ILE336 |
| A | THR338 |
| A | GLU339 |
| A | PHE340 |
| A | MET341 |
| A | SER345 |
| A | LEU393 |
| A | LEU273 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 604 |
| Chain | Residue |
| A | TYR92 |
| A | GLU145 |
| A | GLU147 |
| A | PHE150 |
| A | PHE151 |
| A | SER248 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 605 |
| Chain | Residue |
| A | ARG85 |
| A | ARG123 |
| A | ARG128 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SK8 B 601 |
| Chain | Residue |
| B | LEU273 |
| B | VAL281 |
| B | ALA293 |
| B | LYS295 |
| B | ILE336 |
| B | THR338 |
| B | GLU339 |
| B | PHE340 |
| B | MET341 |
| B | SER345 |
| B | LEU393 |
| B | ASP404 |
| B | GOL605 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 602 |
| Chain | Residue |
| B | ASN391 |
| B | ASP404 |
| B | HOH733 |
| B | HOH749 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 603 |
| Chain | Residue |
| B | ARG123 |
| B | ARG128 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 604 |
| Chain | Residue |
| B | TYR92 |
| B | GLU145 |
| B | PHE150 |
| B | PHE151 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 605 |
| Chain | Residue |
| B | ALA275 |
| B | GLY276 |
| B | GLY279 |
| B | VAL281 |
| B | LYS295 |
| B | SK8601 |
| B | HOH717 |
| B | HOH750 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 23 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGAGQFGEVWmAtynkhtk...........VAVK |
| Chain | Residue | Details |
| A | LEU273-LYS295 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YIHrDLRAANILV |
| Chain | Residue | Details |
| A | TYR382-VAL394 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P08103","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]} |
