4LT6
Crystal Structure of human poly(A) polymerase gamma
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0031123 | biological_process | RNA 3'-end processing |
| A | 1990817 | molecular_function | poly(A) RNA polymerase activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0031123 | biological_process | RNA 3'-end processing |
| B | 1990817 | molecular_function | poly(A) RNA polymerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 3AT A 601 |
| Chain | Residue |
| A | PHE99 |
| A | VAL246 |
| A | THR316 |
| A | SER324 |
| A | CA602 |
| A | HOH714 |
| A | HOH715 |
| A | HOH726 |
| A | HOH727 |
| A | GLY100 |
| A | SER101 |
| A | ASP112 |
| A | ASP114 |
| A | ASN201 |
| A | VAL205 |
| A | LYS227 |
| A | TYR236 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 602 |
| Chain | Residue |
| A | ASP112 |
| A | ASP114 |
| A | 3AT601 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 3AT B 601 |
| Chain | Residue |
| B | PHE99 |
| B | GLY100 |
| B | SER101 |
| B | ASP114 |
| B | ASN201 |
| B | LYS227 |
| B | TYR236 |
| B | VAL246 |
| B | THR316 |
| B | SER324 |
| B | CA602 |
| B | HOH723 |
| B | HOH724 |
| B | HOH726 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 602 |
| Chain | Residue |
| B | ASP112 |
| B | ASP114 |
| B | 3AT601 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24076191","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Site: {"description":"Interaction with RNA","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
