4LS6
Crystal structure of beta-ketoacyl-ACP synthase II (FabF) I108F mutant from Bacillus subtilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 501 |
| Chain | Residue |
| A | ASN300 |
| A | ALA301 |
| A | GLU348 |
| A | SER393 |
| A | ASN394 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 502 |
| Chain | Residue |
| A | HOH742 |
| A | HOH820 |
| A | LYS206 |
| A | LEU208 |
| A | ASP226 |
| A | HOH704 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 503 |
| Chain | Residue |
| A | ALA67 |
| A | MET70 |
| A | GLN75 |
| A | HOH635 |
| A | HOH788 |
| A | HOH812 |
| A | HOH843 |
| A | HOH851 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 501 |
| Chain | Residue |
| B | ASN300 |
| B | ALA301 |
| B | GLU348 |
| B | SER393 |
| B | ASN394 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| A | ASP55 |
| B | LYS206 |
| B | LEU208 |
| B | ASP226 |
| B | HOH673 |
| B | HOH872 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 503 |
| Chain | Residue |
| B | PRO15 |
| B | LEU16 |
| B | SER32 |
| B | LYS54 |
| B | HOH962 |
| B | HOH965 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 504 |
| Chain | Residue |
| A | PRO131 |
| A | PRO135 |
| B | ASN205 |
| B | HIS267 |
| B | ILE268 |
| B | THR269 |
| B | HOH926 |
| B | HOH1054 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 505 |
| Chain | Residue |
| A | PRO36 |
| B | TYR266 |
| B | ALA270 |
| B | PRO271 |
| B | GLN273 |
| B | TYR312 |
| B | HOH1016 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 506 |
| Chain | Residue |
| A | ASP60 |
| A | TYR61 |
| B | THR210 |
| B | ASN211 |
| B | HOH1074 |
Functional Information from PROSITE/UniProt
| site_id | PS00606 |
| Number of Residues | 17 |
| Details | KS3_1 Ketosynthase family 3 (KS3) active site signature. GVNscTVtACATGtnSI |
| Chain | Residue | Details |
| A | GLY154-ILE170 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 814 |
| Details | Domain: {"description":"Ketosynthase family 3 (KS3)","evidences":[{"source":"PROSITE-ProRule","id":"PRU01348","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"For beta-ketoacyl synthase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01348","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
