4LRQ
Crystal structure of a Low Molecular Weight Phosphotyrosine phosphatase from Vibrio choleraeO395
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| C | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| C | 0006470 | biological_process | protein dephosphorylation |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| D | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| D | 0006470 | biological_process | protein dephosphorylation |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MPO A 201 |
| Chain | Residue |
| A | CYS8 |
| A | ASP122 |
| A | TYR124 |
| C | HOH347 |
| A | MET9 |
| A | GLY10 |
| A | ASN11 |
| A | ILE12 |
| A | CYS13 |
| A | ARG14 |
| A | TYR43 |
| A | HIS44 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | GLY127 |
| A | ARG129 |
| A | GLY130 |
| A | HOH398 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | ILE41 |
| A | GLY42 |
| A | TYR43 |
| A | LYS71 |
| A | HOH392 |
| C | GLY42 |
| C | TYR43 |
| C | SO4203 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MPO B 201 |
| Chain | Residue |
| B | CYS8 |
| B | MET9 |
| B | GLY10 |
| B | ASN11 |
| B | ILE12 |
| B | CYS13 |
| B | ARG14 |
| B | HIS44 |
| B | ASP122 |
| B | TYR124 |
| B | TYR125 |
| D | GLU93 |
| D | HOH348 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 202 |
| Chain | Residue |
| B | GLY126 |
| B | GLY127 |
| B | ARG129 |
| B | GLY130 |
| B | HOH319 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 203 |
| Chain | Residue |
| B | ILE41 |
| B | GLY42 |
| B | LYS71 |
| D | GLY42 |
| D | TYR43 |
| D | SO4203 |
| D | HOH380 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MPO C 201 |
| Chain | Residue |
| A | HOH339 |
| C | CYS8 |
| C | MET9 |
| C | GLY10 |
| C | ASN11 |
| C | ILE12 |
| C | CYS13 |
| C | ARG14 |
| C | HIS44 |
| C | ASP122 |
| C | TYR124 |
| C | TYR125 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 202 |
| Chain | Residue |
| B | LYS59 |
| C | GLY127 |
| C | GLU128 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 203 |
| Chain | Residue |
| A | GLY42 |
| A | TYR43 |
| A | SO4203 |
| A | HOH392 |
| C | GLY42 |
| C | LYS71 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MPO D 201 |
| Chain | Residue |
| B | HOH363 |
| D | CYS8 |
| D | MET9 |
| D | GLY10 |
| D | ASN11 |
| D | ILE12 |
| D | CYS13 |
| D | ARG14 |
| D | HIS44 |
| D | ASP122 |
| D | TYR124 |
| D | TYR125 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 202 |
| Chain | Residue |
| A | LYS59 |
| A | HOH366 |
| D | GLY127 |
| D | GLU128 |
| D | HOH328 |
| D | HOH376 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 203 |
| Chain | Residue |
| B | TYR43 |
| B | SO4203 |
| D | ILE41 |
| D | GLY42 |
| D | LYS71 |
| D | HOH380 |
