Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005200 | molecular_function | structural constituent of cytoskeleton |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005874 | cellular_component | microtubule |
| A | 0007017 | biological_process | microtubule-based process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005200 | molecular_function | structural constituent of cytoskeleton |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005874 | cellular_component | microtubule |
| B | 0007010 | biological_process | cytoskeleton organization |
| B | 0007017 | biological_process | microtubule-based process |
| B | 0046872 | molecular_function | metal ion binding |
| K | 0003777 | molecular_function | microtubule motor activity |
| K | 0005524 | molecular_function | ATP binding |
| K | 0007018 | biological_process | microtubule-based movement |
| K | 0008017 | molecular_function | microtubule binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE GTP A 501 |
| Chain | Residue |
| A | GLY10 |
| A | GLY144 |
| A | THR145 |
| A | GLY146 |
| A | VAL177 |
| A | GLU183 |
| A | ASN206 |
| A | TYR224 |
| A | ASN228 |
| A | ILE231 |
| A | MG502 |
| A | GLN11 |
| A | HOH601 |
| A | HOH603 |
| A | HOH621 |
| A | HOH627 |
| A | HOH629 |
| A | HOH636 |
| A | HOH664 |
| A | HOH810 |
| B | LYS254 |
| A | ALA12 |
| A | GLN15 |
| A | ASP98 |
| A | ALA99 |
| A | ASN101 |
| A | SER140 |
| A | GLY143 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | GTP501 |
| A | HOH601 |
| A | HOH602 |
| A | HOH627 |
| A | HOH636 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | VAL177 |
| A | ARG221 |
| A | TYR224 |
| A | HOH645 |
| A | HOH825 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 504 |
| Chain | Residue |
| A | PRO175 |
| A | LYS394 |
| A | HOH858 |
| B | ASN349 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 505 |
| Chain | Residue |
| A | ARG79 |
| A | PRO89 |
| A | LEU92 |
| A | HOH651 |
| A | HOH652 |
| A | HOH718 |
| A | HOH721 |
| D | PHE150 |
| D | LEU165 |
| D | GLN166 |
| D | HOH305 |
| site_id | AC6 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE GDP B 501 |
| Chain | Residue |
| B | GLY10 |
| B | GLN11 |
| B | CYS12 |
| B | GLN15 |
| B | SER140 |
| B | GLY142 |
| B | GLY143 |
| B | GLY144 |
| B | THR145 |
| B | GLY146 |
| B | SER178 |
| B | GLU183 |
| B | ASN206 |
| B | TYR224 |
| B | ASN228 |
| B | HOH601 |
| B | HOH604 |
| B | HOH606 |
| B | HOH632 |
| B | HOH666 |
| B | HOH672 |
| B | HOH798 |
| B | HOH813 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MES B 502 |
| Chain | Residue |
| A | HOH605 |
| B | ARG158 |
| B | PRO162 |
| B | ASP163 |
| B | ARG164 |
| B | ASN197 |
| B | ASP199 |
| B | ARG253 |
| B | HOH633 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 503 |
| Chain | Residue |
| B | PHE296 |
| B | TYR312 |
| B | ASN339 |
| B | TYR342 |
| B | PHE343 |
| B | SO4509 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 504 |
| Chain | Residue |
| B | ASN54 |
| B | ARG88 |
| B | LYS124 |
| B | GLU125 |
| B | SER128 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 505 |
| Chain | Residue |
| B | ASN197 |
| B | HIS192 |
| B | GLN193 |
| B | GLU196 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 506 |
| Chain | Residue |
| B | THR223 |
| B | GLY225 |
| B | ARG278 |
| B | HOH816 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 507 |
| Chain | Residue |
| B | ARG400 |
| B | HOH741 |
| B | HOH772 |
| D | TRP112 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 508 |
| Chain | Residue |
| B | HIS107 |
| B | TYR108 |
| B | GLN193 |
| B | HOH779 |
| B | HOH812 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 509 |
| Chain | Residue |
| B | PHE296 |
| B | ASP297 |
| B | SER298 |
| B | ASP306 |
| B | ARG308 |
| B | GOL503 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 510 |
| Chain | Residue |
| B | GLY100 |
| B | ASN102 |
| B | LYS105 |
| B | TRP407 |
| B | HOH786 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 201 |
| Chain | Residue |
| B | LYS402 |
| D | ARG23 |
| D | TYR57 |
| D | HOH333 |
| D | HOH383 |
| D | HOH387 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL K 401 |
| Chain | Residue |
| A | HIS406 |
| K | LYS256 |
| K | SER259 |
| K | ASN263 |
| K | ASP279 |
| K | HOH526 |
| K | HOH528 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 K 402 |
| Chain | Residue |
| K | SER88 |
| K | SER89 |
| K | GLY90 |
| K | LYS91 |
| K | THR92 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 K 403 |
| Chain | Residue |
| B | GLU196 |
| K | ARG278 |
| K | SER280 |
| K | LYS281 |
| K | HOH543 |
Functional Information from PROSITE/UniProt
| site_id | PS00227 |
| Number of Residues | 7 |
| Details | TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG |
| Chain | Residue | Details |
| B | GLY142-GLY148 | |
| A | GLY142-GLY148 | |
| site_id | PS00228 |
| Number of Residues | 4 |
| Details | TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI |
| Chain | Residue | Details |
| B | MET1-ILE4 | |
| site_id | PS00411 |
| Number of Residues | 12 |
| Details | KINESIN_MOTOR_1 Kinesin motor domain signature. GKLyLVDLAGSE |
| Chain | Residue | Details |
| K | GLY225-GLU236 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI12 |
| Number of Residues | 7 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
