4LMF

C1s CUB1-EGF-CUB2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
B	0005509	molecular_function	calcium ion binding
C	0005509	molecular_function	calcium ion binding
D	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA A 301

Chain	Residue
A	SER10
A	PRO11
A	TYR13
A	GLN15
A	TYR17
A	THR106
A	GLY107

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 302

Chain	Residue
A	ASP98
A	SER100
A	ASN101
A	GLU45
A	ASP53

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 303

Chain	Residue
A	ASP116
A	ILE117
A	GLU119
A	ASN134
A	PHE135
A	GLY138

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 304

Chain	Residue
A	GLU211
A	ASP221
A	ASP260
A	THR262
A	GLY263
A	GLN264

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 301

Chain	Residue
B	SER174
B	PRO175
B	LYS179
B	TYR181
B	LYS266
B	GLY267

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 302

Chain	Residue
B	GLU45
B	ASP53
B	ASP98
B	SER100
B	ASN101

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 303

Chain	Residue
B	ASP116
B	ILE117
B	GLU119
B	ASN134
B	PHE135
B	GLY138

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 304

Chain	Residue
B	GLU211
B	ASP221
B	ASP260
B	THR262
B	GLY263
B	GLN264

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA C 301

Chain	Residue
C	SER174
C	PRO175
C	TYR177
C	LYS179
C	TYR181
C	LYS266

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA C 302

Chain	Residue
C	ASP53
C	ASP98
C	SER100
C	ASN101

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 303

Chain	Residue
C	ASP116
C	ILE117
C	GLU119
C	ASN134
C	PHE135
C	GLY138

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 304

Chain	Residue
C	GLU211
C	ASP221
C	ASP260
C	THR262
C	GLY263
C	GLN264

---

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA D 301

Chain	Residue
D	SER10
D	PRO11
D	ASN12
D	TYR13
D	GLN15
D	TYR17
D	THR106

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 302

Chain	Residue
D	GLU45
D	ASP53
D	ASP98
D	SER100
D	ASN101

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D 303

Chain	Residue
D	ASP116
D	ILE117
D	GLU119
D	ASN134
D	PHE135
D	GLY138

---

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D 304

Chain	Residue
D	GLU211
D	ASP221
D	ASP260
D	THR262
D	GLY263
D	GLN264

---

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CnNfiggYfCsC

Chain	Residue	Details
A	CYS132-CYS143

---

site_id	PS01187
Number of Residues	26
Details	EGF_CA Calcium-binding EGF-like domain signature. DiNECtdfvdvp.......Cshf....CnNfiggYfC

Chain	Residue	Details
A	ASP116-CYS141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING:

Chain	Residue	Details
A	GLU45
B	GLU45
B	ASP53
B	ASP98
B	ASP116
B	ILE117
B	GLU119
B	ASN134
B	PHE135
B	GLY138
C	GLU45
A	ASP53
C	ASP53
C	ASP98
C	ASP116
C	ILE117
C	GLU119
C	ASN134
C	PHE135
C	GLY138
D	GLU45
D	ASP53
A	ASP98
D	ASP98
D	ASP116
D	ILE117
D	GLU119
D	ASN134
D	PHE135
D	GLY138
A	ASP116
A	ILE117
A	GLU119
A	ASN134
A	PHE135
A	GLY138

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: (3R)-3-hydroxyasparagine => ECO:0000269|PubMed:2141278

Chain	Residue	Details
A	ASN134
B	ASN134
C	ASN134
D	ASN134

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:2141278

Chain	Residue	Details
A	ASN159
B	ASN159
C	ASN159
D	ASN159

---